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Title Models of calcium signalling / Geneviève Dupont, Martin Falcke, Vivien Kirk, James Sneyd.

Published Switzerland : Springer, 2016.


Location Call No. Status
Physical description 1 online resource (xxiii, 436 pages) : illustrations (some color)
Series Interdisciplinary applied mathematics, 0939-6047 ; volume 43
Interdisciplinary applied mathematics ; v. 43.
Springer Mathematics and Statistics eBooks 2016 English+International
Bibliography Includes bibliographical references and index.
Contents Some Background Physiology -- The Calcium Toolbox -- Basic Modeling Principles: Deterministic Models -- Hierarchical and Stochastic Modeling -- Nonlinear Dynamics of Calcium -- Nonexcitable Cells -- Muscle -- Neurons and Other Excitable Cells.
Summary This book discusses the ways in which mathematical, computational, and modelling methods can be used to help understand the dynamics of intracellular calcium. The concentration of free intracellular calcium is vital for controlling a wide range of cellular processes, and is thus of great physiological importance. However, because of the complex ways in which the calcium concentration varies, it is also of great mathematical interest. This book presents the general modelling theory as well as a large number of specific case examples, to show how mathematical modelling can interact with experimental approaches, in an interdisciplinary and multifaceted approach to the study of an important physiological control mechanism. Geneviève Dupont is FNRS Research Director at the Unit of Theoretical Chronobiology of the Université Libre de Bruxelles;Martin Falcke is head of the Mathematical Cell Physiology group at the Max Delbrück Center for Molecular Medicine, Berlin;Vivien Kirk is an Associate Professor in the Department of Mathematics at the University of Auckland, New Zealand; James Sneyd is a Professor in the Department of Mathematics at The University of Auckland, New Zealand.
Other author Dupont, Geneviève, author.
Falcke, M., 1961- author.
Kirk, Vivien, author.
Sneyd, James, author.
SpringerLink issuing body.
Subject Intracellular calcium -- Mathematical models.
Cellular signal transduction -- Mathematical models.
Electronic books.
ISBN 9783319296470 (electronic bk.)
3319296477 (electronic bk.)
9783319296456 (print)
Standard Number 10.1007/978-3-319-29647-0