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008 140516s2014 dcua ob 100 0 eng c
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060 00 2014 K-350
060 00 QU 460
082 04 572.8/6|223
100 1 Beachy, Sarah H.,|eauthor.
245 10 Improving the efficiency and effectiveness of genomic
science translation :|bworkshop summary /|cSarah H. Beachy,
Samuel G. Johnson, Steve Olson, and Adam C. Berger,
rapporteurs ; Roundtable on Translating Genomic-Based
Research for Health, Board on Health Sciences Policy,
Institute of Medicine of the National Academies.
264 1 Washington, D.C. :|bNational Academies Press,|c
300 1 online resource (1 PDF file (xx, 67 pages)) :
338 online resource|bcr|2rdacarrier
500 Title from PDF title page.
504 Includes bibliographical references.
505 0 Introduction -- Connecting basic research and health care
needs -- Moving basic science forward -- Industry and
venture capital -- Role of advocacy in facilitating
translation of basic scientific research -- Strategies for
520 "The process for translating basic science discoveries
into clinical applications has historically involved a
linear and lengthy progression from initial discovery to
preclinical testing, regulatory evaluation and approval,
and, finally, use in clinical practice. The low rate of
translation from basic science to clinical application has
been a source of frustration for many scientists,
clinicians, investors, policy makers, and patients who
hoped that investments in research would result in
improved products and processes for patients. Some feel
that the anticipated deliverables from the Human Genome
Project have not yet materialized, and although
understanding of human health and disease biology has
increased, there has not been a concomitant increase in
the number of approved drugs for patients over the past 10
years. Improving the Efficiency and Effectiveness of
Genomic Science Translation is the summary of a workshop
convened by the Institute of Medicine Roundtable on
Translating Genomic-Based Research for Health in December
2012 to explore ways to improve the efficiency and
effectiveness of the translation of genomic science to
clinical practice. The workshop convened academic
researchers, industry representatives, policy makers, and
patient advocates to explore obstacles to the translation
of research findings to clinical practice and to identify
opportunities to support improvement of the early stages
of the process for translation of genetic discoveries.
This report discusses the realignment of academic
incentives, the detection of innovative ways to fund
translational research, and the generation or
identification of alternative models that accurately
reflect human biology or disease to provide opportunities
to work across sectors to advance the translation of
genomic discoveries"--Publisher's description.
650 0 Medical care|xResearch|vCongresses.
650 0 Genomics|vCongresses.
655 2 Congresses.
655 4 Electronic books.
655 7 Conference papers and proceedings.|2fast
700 1 Johnson, Samuel G.,|eauthor.
700 1 Olson, Steve,|d1956-|eauthor.
700 1 Berger, Adam C.,|eauthor.
710 2 Institute of Medicine (U.S.).|bRoundtable on Translating
Genomic-Based Research for Health,|eissuing body.
710 2 National Library of Medicine|eissuing body.
711 2 Improving the Efficiency and Effectiveness of Genomic
Science Translation (Workshop)|d(2012 :|cIrvine, Calif.)
776 08 |iPrint version:|tImproving the efficiency and
effectiveness of genomic science translation.|dWashington,
D.C. : National Academies Press, 2014|z0309294533
830 0 NCBI BookShelf
856 40 |uhttp://www.ncbi.nlm.nih.gov/books/NBK201429|zConnect to
ebook (University of Melbourne only)
990 National Center for Biotechnology Information
990 Batch Ebook load (bud2) - do not edit, delete or attach
991 |zNEW New collection NLM.bookshelf 2018-08-03