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LEADER 00000cam a2200637 i 4500 
003    OCoLC 
005    20180804040830.3 
006    m     o  d         
007    cr cn||||||||| 
008    140516s2014    dcua    ob    100 0 eng c 
019    NCBIBSocn881362878 
020    9780309294539 
020    0309294533 
020    9780309294546 
020    0309294541 
040    YDXCP|beng|erda|epn|cNLM|dMMU|dOCLCF|dCUS|dC6I|dN$T|dYDXCP
042    pcc 
043    n-us--- 
049    MAIN 
050  4 QH447 
060 00 2014 K-350 
060 00 QU 460 
082 04 572.8/6|223 
100 1  Beachy, Sarah H.,|eauthor. 
245 10 Improving the efficiency and effectiveness of genomic 
       science translation :|bworkshop summary /|cSarah H. Beachy,
       Samuel G. Johnson, Steve Olson, and Adam C. Berger, 
       rapporteurs ; Roundtable on Translating Genomic-Based 
       Research for Health, Board on Health Sciences Policy, 
       Institute of Medicine of the National Academies. 
264  1 Washington, D.C. :|bNational Academies Press,|c[2014] 
300    1 online resource (1 PDF file (xx, 67 pages)) :
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
500    Title from PDF title page. 
504    Includes bibliographical references. 
505 0  Introduction -- Connecting basic research and health care 
       needs -- Moving basic science forward -- Industry and 
       venture capital -- Role of advocacy in facilitating 
       translation of basic scientific research -- Strategies for
520    "The process for translating basic science discoveries 
       into clinical applications has historically involved a 
       linear and lengthy progression from initial discovery to 
       preclinical testing, regulatory evaluation and approval, 
       and, finally, use in clinical practice. The low rate of 
       translation from basic science to clinical application has
       been a source of frustration for many scientists, 
       clinicians, investors, policy makers, and patients who 
       hoped that investments in research would result in 
       improved products and processes for patients. Some feel 
       that the anticipated deliverables from the Human Genome 
       Project have not yet materialized, and although 
       understanding of human health and disease biology has 
       increased, there has not been a concomitant increase in 
       the number of approved drugs for patients over the past 10
       years. Improving the Efficiency and Effectiveness of 
       Genomic Science Translation is the summary of a workshop 
       convened by the Institute of Medicine Roundtable on 
       Translating Genomic-Based Research for Health in December 
       2012 to explore ways to improve the efficiency and 
       effectiveness of the translation of genomic science to 
       clinical practice. The workshop convened academic 
       researchers, industry representatives, policy makers, and 
       patient advocates to explore obstacles to the translation 
       of research findings to clinical practice and to identify 
       opportunities to support improvement of the early stages 
       of the process for translation of genetic discoveries. 
       This report discusses the realignment of academic 
       incentives, the detection of innovative ways to fund 
       translational research, and the generation or 
       identification of alternative models that accurately 
       reflect human biology or disease to provide opportunities 
       to work across sectors to advance the translation of 
       genomic discoveries"--Publisher's description. 
650  0 Medical care|xResearch|vCongresses. 
650  0 Genomics|vCongresses. 
655  2 Congresses. 
655  4 Electronic books. 
655  7 Conference papers and proceedings.|2fast
700 1  Johnson, Samuel G.,|eauthor. 
700 1  Olson, Steve,|d1956-|eauthor. 
700 1  Berger, Adam C.,|eauthor. 
710 2  Institute of Medicine (U.S.).|bRoundtable on Translating 
       Genomic-Based Research for Health,|eissuing body. 
710 2  National Library of Medicine|eissuing body. 
711 2  Improving the Efficiency and Effectiveness of Genomic 
       Science Translation (Workshop)|d(2012 :|cIrvine, Calif.) 
776 08 |iPrint version:|tImproving the efficiency and 
       effectiveness of genomic science translation.|dWashington,
       D.C. : National Academies Press, 2014|z0309294533
830  0 NCBI BookShelf 
856 40 |u|zConnect to 
       ebook (University of Melbourne only) 
990    National Center for Biotechnology Information 
990    Batch Ebook load (bud2) - do not edit, delete or attach 
       any records. 
991    |zNEW New collection NLM.bookshelf 2018-08-03 
Location Call No. Status