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LEADER 00000cam a2200505Ii 4500 
003    OCoLC 
005    20190427060103.1 
006    m     o  d         
007    cr cnu|||unuuu 
008    190329s2019    sz      ob    001 0 eng d 
019    SpringerEBAon1090813000 
020    9783030026349|q(electronic bk.) 
020    3030026345|q(electronic bk.) 
020    |z9783030026332 
040    N$T|beng|erda|epn|cN$T|dN$T|dEBLCP|dGW5XE 
049    MAIN 
050  4 QH324.2 
082 04 570.285|223 
245 00 Essentials of bioinformatics.|nVolume I,|pUnderstanding 
       bioinformatics: genes to proteins /|cNoor Ahmad Shaik, 
       Khalid Rehman Hakeem, Babajan Banaganapalli and Ramu 
       Elango, editors. 
246 30 Understanding bioinformatics: genes to proteins 
264  1 Cham, Switzerland :|bSpringer Nature,|c[2019] 
300    1 online resource. 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
504    Includes bibliographical references and index. 
505 0  Intro; Foreword; Preface; Contents; About the Editors; 
       Chapter 1: Introduction to Bioinformatics; 1.1 
       Introduction; 1.2 The Role of Bioinformatics in Gene 
       Expression Data Analysis; 1.3 The Role of Bioinformatics 
       in Gene/Genome Mapping; 1.4 Role of Bioinformatics 
       in Sequence Alignment and Similarity Search; 1.5 
       Contribution of Bioinformatics toward Modern Cancer 
       Research; 1.6 The Domain of Structural Bioinformatics; 1.7
       Bioinformatics Processing of Big Data; 1.8 Conclusion; 
       References; Chapter 2: Introduction to Biological 
       Databases; 2.1 Introduction to Databases; 2.2 Types 
       of Databases 
505 8  2.2.1 Relational Databases2.2.2 Object-Oriented Database; 
       2.3 Introduction to Biological Databases; 2.3.1 
       Classification of Biological Databases; 2.3.2 Primary 
       Database; 2.3.3 Secondary Databases; 2.3.4 Specialized 
       Databases; 2.3.5 Interconnection between Biological 
       Databases; 2.4 Retrieval from Databases; 2.5 Conclusion; 
       References; Chapter 3: Sequence Databases; 3.1 
       Introduction; 3.2 Sequence Data Generation; 3.2.1 The 
       First Generation of Sequencing; 3.2.2 The Second 
       Generation of Sequencing; 3.2.3 The Third Generation 
       of Sequencing; 3.3 Classes of Biological Databases 
505 8  3.4 Types of Sequence Databases3.4.1 Nucleotide Sequence 
       Databases; 3.4.1.1 EMBL/DDBJ/GenBank; 3.4.1.2 RefSeq; 
       3.4.1.3 Ensembl; 3.4.2 Protein Sequence Database; 3.4.2.1 
       TrEMBL; 3.4.2.2 GenPept; 3.4.2.3 Entrez Protein; 3.4.2.4 
       UniProt; 3.5 Sequence Submission; 3.5.1 Sequin; 3.5.2 
       BankIt; 3.5.3 Webin; 3.6 Retrieval; 3.6.1 SRS (Sequence 
       Retrieval System); 3.6.2 Entrez; 3.6.3 DBGET; 3.7 
       Conclusion; References; Chapter 4: Biological 3D 
       Structural Databases; 4.1 Introduction; 4.1.1 X-Ray 
       Crystallography; 4.1.2 Crystal Formation; 4.1.3 Structure 
       Determination; 4.2 Macromolecular Structural Databases 
505 8  4.2.1 Protein Data Bank wwPDB4.2.1.1 RCSB PDB; 4.3 PDBsum:
       Structural Summaries of PDB Entries; 4.4 sc-PDB: A 3D 
       Database of Ligandable Binding Sites; 4.5 PDBTM: Protein 
       Data Bank of Transmembrane Proteins; 4.6 CATH Database; 
       4.7 SCOP (Structural Classification of Proteins) Database;
       4.8 Structure Comparison Servers; 4.9 Conclusion; 
       References; Chapter 5: Other Biological Databases; 5.1 
       Introduction; 5.2 Gene or Genome Annotation Databases; 
       5.2.1 GO/GOA Databases; 5.2.2 UCSC Genome Browser: 
       Annotation Database; 5.3 Protein Annotation Databases; 
       5.3.1 PRIDE Archive; 5.3.2 SWISS-2DPAGE 
505 8  5.3.3 Domain Databases5.4 Network Databases; 5.4.1 IntAct;
       5.5 Pathway Databases; 5.5.1 Kyoto Encyclopedia of Genes 
       and Genomes; 5.5.2 BioCyc; 5.5.3 Ingenuity Pathways 
       Knowledge Base; 5.5.4 Reactome Pathway Databases; 5.5.5 
       Other Pathway Databases; 5.6 Drug Databases; 5.6.1 
       DrugBank; 5.6.2 PharmGKB; 5.6.3 ChEBI; 5.6.4 PubChem; 
       5.6.5 ZINC Database; 5.7 Specialized Database; 5.7.1 Model
       Organism Databases; 5.7.2 IntEnz; 5.7.3 EPD; 5.7.4 
       TRANSFAC; 5.8 Scientific Literature Database; 5.8.1 
       PubMed; 5.8.2 SCI (Science Citation Index); 5.8.3 Google 
       Scholar; 5.9 Conclusion; References 
520    Bioinformatics is an integrative field of computer science,
       genetics, genomics, proteomics, and statistics, which has 
       undoubtedly revolutionized the study of biology and 
       medicine in past decades. It mainly assists in modeling, 
       predicting and interpreting large multidimensional 
       biological data by utilizing advanced computational 
       methods. Despite its enormous potential, bioinformatics is
       not widely integrated into the academic curriculum as most
       life science students and researchers are still not 
       equipped with the necessary knowledge to take advantage of
       this powerful tool. Hence, the primary purpose of our book
       is to supplement this unmet need by providing an easily 
       accessible platform for students and researchers starting 
       their career in life sciences. This book aims to avoid 
       sophisticated computational algorithms and programming. 
       Instead, it mostly focuses on simple DIY analysis and 
       interpretation of biological data with personal computers.
       Our belief is that once the beginners acquire these basic 
       skillsets, they will be able to handle most of the 
       bioinformatics tools for their research work and to better
       understand their experimental outcomes.Unlike other 
       bioinformatics books which are mostly theoretical, this 
       book provides practical examples for the readers on state-
       of-the-art open source tools to solve biological 
       problems. Flow charts of experiments, graphical 
       illustrations, and mock data are included for quick 
       reference. Volume I is therefore an ideal companion for 
       students and early stage professionals wishing to master 
       this blooming field. 
650  0 Bioinformatics. 
655  0 Electronic books. 
655  4 Electronic books. 
700 1  Shaik, Noor Ahmad,|eeditor. 
700 1  Hakeem, Khalid Rehman,|eeditor. 
700 1  Banaganapalli, Babjan,|eeditor. 
700 1  Ramu, Elango,|eeditor. 
710 2  SpringerLink|eissuing body. 
830  0 Springer Biomedical and Life Sciences eBooks 2019 English+
       International 
856 40 |uhttps://ezp.lib.unimelb.edu.au/login?url=http://
       link.springer.com/10.1007/978-3-030-02634-9|zConnect to 
       ebook (University of Melbourne only) 
990    Springer Biomedical and Life Sciences eBooks 2019 - Full 
       Set 
990    Batch Ebook load (bud2) - do not edit, delete or attach 
       any records. 
991    |zNEW Added to collection springerlink.ebooksbls2019 2019-
       04-26 
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