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Title Ex vivo engineering of the tumor microenvironment / Amir R. Aref, David Barbie, editors.

Published Cham : Humana Press, [2017]


Location Call No. Status
Physical description 1 online resource.
Series Cancer drug discovery and development.
Cancer drug discovery and development.
Springer Medicine eBooks 2017 English+International.
Bibliography Includes bibliographical references.
Contents 1. Introduction to Ex Vivo Cancer Models -- 2. Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5. Advancing techniques and insights in circulating tumor cell (CTC) research -- 6. The Cancer Secretome -- 7. An overview of the tumor microenvironments and future of cancer therapy.
Summary This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.
Other author Aref, Amir R., editors.
Barbie, David, editor.
SpringerLink (Online service), issuing body.
Subject Cancer -- Molecular aspects.
Tumors -- Molecular aspects.
Electronic books.
Standard Number 10.1007/978-3-319-45397-2
ISBN 9783319453972 (electronic bk.)
3319453971 (electronic bk.)