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Author Debyser, Zeger, (Laboratory for Molecular Virology and Gene Therapy, K.U.Leuven, Belgium) Speaker.

Title Cellular cofactors of HIV integrase [electronic resource] : from target identification to discovery of ledgins / Zeger Debyser.

Published London : Henry Stewart Talks, 2011.


Location Call No. Status
Physical description 1 streaming video file (52 min.) : digital, mono., SWF file, sd., col.
Series Antivirals : latest developments and future progress
Henry Stewart talks. Biomedical & life sciences collection. Antivirals
Notes Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents Contents: Cellular cofactors of HIV as novel antiviral targets -- LEDGF/p75 is a tethering factor of HIV integrase -- Identification of LEDGF/p75 as binding partner of integrase -- Characterization of the interaction -- Validation of integrase -- LEDGF/p75 interaction as antiviral target -- Assay and Drug Development -- Transportin -- SR2 is a nuclear import factor.
Restrictions Access restricted to subscribers.
System notes Mode of access: World Wide Web.
System requirements: Operating System: PC Windows 2000+, Mac OSX+ 3.2. Browser Compatibility: IE6+, Firefox 2+, Opera 9+, Safari 2+ 3.3. Browser settings: enable JavaScript, enable popups from the Henry Stewart Talks site. 3.4. Required Browser Plugins & Viewers: Adobe (Macromedia) Flash Player 7+, Adobe Acrobat Reader 6.0+.
Subject HIV infections -- Chemotherapy.
Antiviral agents.
Virus diseases -- Chemotherapy.