My Library

University LibraryCatalogue


LEADER 00000cam a2200613Ii 4500 
003    OCoLC 
005    20190319055456.4 
006    m     o  d         
007    cr cnu|||unuuu 
008    170317s2017    sz      ob    000 0 eng d 
015    GBB8N7339|2bnb 
019    SpringerEBAocn976406732 
020    9783319529455|q(electronic bk.) 
020    3319529455|q(electronic bk.) 
020    |z9783319529431|q(print) 
020    |z3319529439 
024 7  10.1007/978-3-319-52945-5|2doi 
037    com.springer.onix.9783319529455|bSpringer Nature 
040    N$T|beng|erda|epn|cN$T|dEBLCP|dGW5XE|dYDX|dN$T|dOCLCF|dDKU
       |dOCLCO|dCOO|dAZU|dUPM|dOCLCO|dMERER|dVT2|dOCLCQ|dOCLCO
       |dOCLCQ|dOCLCO|dJG0|dOCLCO|dOCLCA|dUAB|dOCLCO|dIOG|dU3W
       |dCAUOI|dICW|dOCLCQ|dKSU|dOCLCO|dOCLCQ|dAU@|dOCLCO|dOCLCQ
       |dESU|dWYU|dLVT|dOCLCO|dOCLCA|dOCLCQ|dOCLCO|dUKMGB|dOCLCO 
049    MAIN 
050  4 QP623 
060  4 QU 58.7 
082 04 572.8/8|223 
082 04 610 
245 00 Non-coding RNAs in the vasculature /|cThomas Thum, 
       Stefanie Dimmeler, editors. 
264  1 Cham, Switzerland :|bSpringer,|c2017. 
300    1 online resource. 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
347    text file|bPDF|2rda 
490 1  Cardiac and vascular biology,|x2509-7830 
504    Includes bibliographical references. 
505 0  Preface; Contents; 1: Regulation of Atherosclerosis by 
       microRNAs; 1.1 Introduction; 1.2 miRNA-Mediated Regulatory
       Mechanisms; 1.2.1 Regulatory Mechanisms of miRNA Strands 
       Derived from a Single Precursor; 1.2.2 RNA Sponges in the 
       Regulation of miRNA Activity; 1.2.3 Circulating miRNAs: 
       Messengers on the Move; 1.3 Regulation of Inflammatory 
       Macrophage Activation by a miRNA Tandem; 1.4 Combined 
       Roles of miR-126-3p and miR-126-5p in Endothelial 
       Regeneration and Their Use in Therapeutic Approaches; 1.5 
       Lipoprotein-Mediated miRNA Transfer; 1.6 Conclusions and 
       Future Work; References. 
505 8  2: Noncoding RNAs in Cholesterol Metabolism and 
       Atherosclerosis2.1 Introduction; 2.2 miRNAs Regulating HDL
       -C Metabolism and Reverse Cholesterol Transport; 2.2.1 miR
       -33a/miR-33b; 2.2.2 miR-33a/miR-33b and Atherosclerosis; 
       2.3 miRNAs and LDL-C Metabolism; 2.3.1 miRNAs That 
       Regulate Cholesterol Biosynthesis and VLDL Secretion; 
       2.3.1.1 miR-122; 2.3.1.2 miR-30c in Lipid Metabolism and 
       Atherosclerosis; 2.3.1.3 miR-33a/miR-33b; 2.3.1.4 miR-96/
       miR-182/miR-183; 2.3.2 miRNAs That Regulate LDLR 
       Expression and LDL-C Clearance; 2.3.2.1 miR-148a; 2.3.2.2 
       miR-128-1; 2.3.2.3 miR-185. 
505 8  2.4 LncRNAs and Cholesterol Metabolism2.4.1 LeXis; 2.4.2 
       Lnc-HC and ApoA1-AS; 2.4.3 LncLSTR; 2.5 Concluding 
       Remarks; References; 3: MicroRNAs in Diabetes and Its 
       Vascular Complications; 3.1 Introduction; 3.2 MicroRNAs in
       Diabetes Mellitus; 3.2.1 Pancreas; 3.2.2 Adipose Tissue; 
       3.2.3 Muscle; 3.2.4 Liver; 3.3 MicroRNAs Modulating the 
       Impact of Diabetes Mellitus on Bone Marrow and on Stem and
       Progenitor Cells; 3.4 MicroRNAs in Diabetic Cardiovascular
       Complications; 3.4.1 Microvascular Complications; 3.4.1.1 
       Nephropathy; 3.4.1.2 Retinopathy; 3.4.1.3 Neuropathy. 
505 8  3.4.2 Cardiac Disease3.4.3 Peripheral Vascular Disease; 
       3.5 MicroRNA as Circulating Biomarkers of Diabetic 
       Cardiovascular Disease; 3.6 Concluding Remarks; 
       References; 4: Noncoding RNAs in Ischemic Cardiovascular 
       Disease and Repair Mechanisms; 4.1 Targeting miRNAs to 
       Enhance Cell-Based Therapies; 4.2 Targeting miRNAs to 
       Induce a Cardiac Phenotype in Pluripotent Stem Cells; 4.3 
       Targeting miRNAs to Facilitate Cardiac Regenerative 
       Pathways; 4.4 MiRNAs in the Development and Progression of
       Heart Failure; 4.5 Long Noncoding RNAs in Cardiovascular 
       Disease; References. 
505 8  5: Circulating microRNAs as Novel Biomarkers in 
       Cardiovascular Disease: Basic and Technical Principles5.1 
       Introduction; 5.2 MicroRNA Biogenesis and Function; 5.3 
       Circulating miRNAs; 5.3.1 miRNAs in Vesicles; 5.3.1.1 
       Apoptotic Bodies; 5.3.1.2 Microparticles; 5.3.1.3 
       Exosomes; 5.3.2 miRNAs in Protein Complexes; 5.3.3 miRNAs 
       in Lipoprotein Complexes; 5.4 Quantification of 
       Circulating miRNAs; 5.4.1 Sample Preparation; 5.4.1.1 
       Sample Processing and Handling; 5.4.1.2 RNA Isolation; 
       5.4.2 Data Normalisation; 5.4.3 Comprehensive Profiling of
       Circulating miRNAs. 
520    This book focuses on the importance of regulatory RNAs in 
       the vasculature. The main topics discussed include the 
       role of regRNAs in vascular development and angiogenesis, 
       ischemic cardiovascular disease and repair mechanisms, 
       diabetic and metabolic vascular disease, atherosclerosis 
       and vascular inflammation, as well as diagnostics of 
       vascular disease using circulating miRNAs. Lastly, it 
       offers an overview of emerging topics such as microvesicle
       -mediated miRNA cellular trafficking and the vascular 
       importance of long non-coding RNAs. It is an invaluable 
       resource for academics, researchers and students working 
       in the field of vascular biology. 
650  0 Non-coding RNA. 
655  4 Electronic books. 
700 1  Thum, Thomas,|eeditor. 
700 1  Dimmeler, Stefanie,|eeditor. 
710 2  SpringerLink|eissuing body. 
776 08 |iPrint version:|tNon-coding RNAs in the vasculature.
       |dCham, Switzerland : Springer, 2017|z3319529439
       |z9783319529431|w(OCoLC)967374866 
830  0 Cardiac and vascular biology. 
830  0 Springer Biomedical and Life Sciences eBooks 2017 English+
       International 
856 40 |uhttps://ezp.lib.unimelb.edu.au/login?url=http://
       link.springer.com/10.1007/978-3-319-52945-5|zConnect to 
       ebook (University of Melbourne only) 
990    Springer EBA e-book collections for 2017-2019 
990    Springer Biomedical and Life Sciences eBooks 2017 - Full 
       Set 
990    Batch Ebook load (bud2) - do not edit, delete or attach 
       any records. 
991    |zNEW New collection springerlink.ebooksbls2017 2019-03-18
Location Call No. Status
 UniM INTERNET resource    AVAILABLE