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Title Gas mixing and distribution in the lung / edited by Ludwig A. Engel, Manuel Paiva.

Published New York : Dekker, [1985]


Location Call No. Status
 UniM BioMed ST  599.012 GAS    AVAILABLE
Physical description xi, 416 pages : illustrations ; 24 cm.
Series Lung biology in health and disease ; v. 25.
Lung biology in health and disease ; v. 25.
Bibliography Includes bibliographies and indexes.
Contents 1. General Concepts of Molecular Diffusion / H. K. Chang 1 -- II. General Description of Gaseous Diffusion 3 -- III. Physical Basis of Molecular Diffusion 4 -- IV. Phenomenological Laws of Molecular Diffusion 8 -- 2. Anatomical Factors Influencing Gas Mixing and Distribution / Keith Horsfield 23 -- II. Conducting Airways 24 -- III. Acinus 43 -- IV. Airway Cross-Sectional Area 49 -- V. Asymmetry and Function 49 -- VI. Diseased Lungs 50 -- 3. Gas Transport in the Conducting Airways / James S. Ultman 63 -- III. Theoretical Basis of Mixing Experiments 86 -- IV. Mixing Experiments 98 -- V. Applications 117 -- 4. Alveolar Ventilation at High Frequencies Using Tidal Volumes Smaller than the Anatomical Dead Space / Arthur S. Slutsky, Roger D. Kamm, Jeffrey M. Drazen 137 -- II. Historical Review 138 -- III. Mechanisms of Gas Transport 141 -- IV. Measurements of Gas Transport in Hardware Models 151 -- V. Theories of Gas Exchange During HFV 155 -- VI. Physiological Studies 161 -- 5. Regional Ventilation Distribution / J. M. B. Hughes, Terence C. Amis 177 -- II. Theory and Methods 178 -- III. Distribution of Ventilation in Normal Subjects 183 -- IV. Regional Lung Expansion in Normal Subjects 191 -- V. Residual Volume 197 -- VI. Anesthesia and Muscle Paralysis 200 -- VII. Distribution of Ventilation in Lung Disease 204 -- VIII. Mechanisms 207 -- 6. Theoretical Studies of Gas Mixing in the Lung / Manuel Paiva 221 -- II. Diffusion Equation 225 -- III. Trumpet Model 232 -- IV. Two-Trumpet or One-Branch-Point Model 253 -- V. Multibranch-Point Models 272 -- 7. Intraregional Gas Mixing and Distribution / Ludwig A. Engel 287 -- II. Historical Aspects 288 -- III. Mechanisms of Gas Mixing 289 -- IV. Potential Mechanisms of Gas Mixing Inhomogeneity 290 -- V. Single-Breath Inert Gas Washout 295 -- VI. Multiple-Breath Inert Gas Washout 311 -- VII. Other Experimental Approaches 342 -- 8. Distribution and Mixing in Gas-Exchange Organs of Nonmammalian Vertebrates / Peter Scheid, Johannes Piiper 359 -- II. Birds 360 -- III. Fish 374 -- IV. Mammals versus Birds and Fish: Search for Similarities 383.
Summary This impressive volume presents a state-of-the-art synthesis of all aspects of gas mixing and ventilation distribution in the lung, blending current theoretical understanding with the most recent experimental findings for complete coverage unavailable in any other single source. Written by an international panel of renowned physiologists, physicists, engineers, and physicians, Gas Mixing and Distribution in the Lung examines basic principles of molecular diffusion, plus lung anatomy and how it influences gas mixing and distribution ... mathematical and computer models being developed to better understand gas mixing in the lung -- an area of rapid, exciting advances ... dispersion of gases in conducting airways, as well as mechanisms for axial dispersion that sustain alveolar ventilation and gas exchange at high-frequency ventilation ... regional ventilation distribution -- where improvements in the use of radioactive gas isotopes and imaging facilities are providing new findings ... topics in comparative physiology, respiratory disease states, and more. Gathering the widely scattered, multidisciplinary knowledge in one well-illustrated and fully referenced resource, this comprehensive volume provides the authoritative insight into the subject required by pulmonary physiologists, pneumologists, anesthesiologists, biomedical engineers, biophysicists, physiotherapists, nuclear medicine specialists, inhalation therapists, and medical students. Also, the book is an excellent reference for graduate-level courses in Respiratory Physiology or Comparative Physiology.
Other author Engel, Ludwig A., 1938-
Paiva, Manuel, 1943-
Subject Pulmonary gas exchange.
ISBN 0824772849