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Title NF-[kappa]B-related genetic diseases / Gilles Courtois, Alessandra Pescatore, Jérémie Gautheron, Francesca Fusco, Matilde Valeria Ursini, Anna Senegas.

Published [Cham] : Springer, 2016.


Location Call No. Status
Physical description 1 online resource (xii, 70 pages) : illustrations.
Series SpringerBriefs in biochemistry and molecular biology, 2211-9353
SpringerBriefs in biochemistry and molecular biology, 2211-9353
Springer English/International eBooks 2016 - Full Set
Springer Biomedical and Life Sciences eBooks 2016 English+International
Bibliography Includes bibliographical references.
Contents 1) The NF-kB signaling pathways: players and Functions -- 2) Genetic Diseases Affecting the Canonical Pathway of NF-kB Activation -- 3) Genetic Diseases Affecting hte Non-Camonical Pathway of NF-kB Activation -- 4) Genetic Diseases Affecting Ubiquitination Processes in NF-kB Signaling -- 5)Lessons Learned from Studying NF-kB Related Genetic Diseases.
Summary This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis of the pathophysiological processes.
Other author Courtois, Gilles, author.
Pescatore, Alessandra, author.
Gautheron, Jérémie, author.
Fusco, Francesca, author.
Ursini, Matilde Valeria, author.
Senegas, Anna, author.
SpringerLink issuing body.
Subject Genetic disorders.
NF-kappa B (DNA-binding protein)
Electronic books.
Electronic books.
ISBN 9783319258508 electronic bk.
3319258508 electronic bk.
Standard Number 10.1007/978-3-319-25850-8