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Title Advances in systems biology / edited by Julie M. Gephart, Lee K. Opresko, and Michaela B. Mann.

Published New York : Kluwer Acadamic/Plenum, 2004.


Location Call No. Status
 UniM BioMed  571 ADVA    AVAILABLE
Physical description ix, 108 pages : illustrations ; 26 cm.
Series Advances in experimental medicine and biology ; v. 547.
Advances in experimental medicine and biology ; v. 547.
Bibliography Includes bibliographical references and index.
Contents 1. Introduction : about the northwest symposium for systems biology / Lee K. Opresko and H. Steven Wiley -- Complex microbial systems -- 2. High-throughput techniques for analyzing complex bacterial communities / David A. Stahl -- Computational methods -- 3. A systems approach to discovering signaling and regulatory pathways - or how to digest large interaction networks into relevant pieces / Trey Ideker -- 4. Genome function - a virus-world view / John Yin -- Molecular machines : multiprotein complexes -- 5. Intracellular proteolysis and proteasomes / Martin C. Rechsteiner -- 6. Conformational switching in muscle / Piotr Fajer -- Gene regulatory networks -- 7. The intricate workings of a bacterial epigenetic switch / David Low -- 8. Yeast signal transduction : regulation and interface with cell biology / George F. Sprague.
Summary This book is based on the proceedings of the inauguralsymposium "Northwest Symposium for Systems Biology." Particular focusis on identifying current breakthrough technologies and theirapplication to important model systems. By integrating computationalsciences, high-throughput technologies and quantitative biology, thisbook will advance the understanding of not just the function ofindividual genes, proteins and smaller molecules like hormones, butalso how all of these molecules interact within a cell.This volume will be a collection of presentations on four topics thatcomprise the scope of the Genomes to Life project recently announcedby the Department of Energy. They are four aspects of a system biologyapproach to understanding microbial communities. These topics includecomplex microbial systems, gene regulatory networks, molecularmachines/ multiprotein complexes and computational techniques. Therange of material covered will include the following:
Other author Opresko, Lee.
Gephart, Julie M.
Mann, Michaela B.
Subject Biological systems.
ISBN 0306483149