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LEADER 00000nam  2200493 i 4500 
003    MiAaPQ 
006    m     o  d |       
007    cr cnu|||||||| 
008    160715t20172017njua    ob    001 0 eng|d 
019    PQacadEBC4745624 
020    |z9781119060680|q(cloth) 
020    |z9781119060680 
020    9781119060802|q(e-book) 
035    (MiAaPQ)EBC4745624 
035    (Au-PeEL)EBL4745624 
035    (CaPaEBR)ebr11300198 
035    (CaONFJC)MIL978150 
035    (OCoLC)964410742 
040    MiAaPQ|beng|erda|epn|cMiAaPQ|dMiAaPQ 
050  4 RS431.A64|bA58 2017 
082 0  615.7/98|223 
130 0  Antibody-drug conjugates (Olivier) 
245 10 Antibody-drug conjugates :|bfundamentals, drug development,
       and clinical outcomes to target cancer /|cedited by 
       Kenneth J. Olivier Jr. and Sara A. Hurvitz. 
264  1 Hoboken, New Jersey :|bJohn Wiley & Sons, Incorporated,
       |c[2017] 
264  4 |c©2017 
300    1 online resource (566 pages) :|bcolor illustrations 
336    text|2rdacontent 
337    computer|2rdamedia 
338    online resource|2rdacarrier 
504    Includes bibliographical references and index. 
505 0  Typical antibody-drug conjugates / John Lambert -- 
       Selecting optimal ADC targets using indication-dependent 
       or indication-independent approaches / Robert 
       Hollingsworth and Jay Harper -- Antibody drug conjugates :
       an overview of the CMC and characterization process / 
       Janet Wolfe and Phillip Ross -- Linker and conjugation 
       technology and improvements / Riley Ennis and Sourav Sinha
       -- Formulation and stability / Kouhei Tsumoto, Anthony 
       Young, and Satoshi Ohtake -- QC assay development / Xiao-
       Hong Chen and Mate Tolnay -- Occupational health and 
       safety aspects of ADCs and their toxic payloads / Robert 
       Sussman and John Farris -- Bioanalytical strategies 
       enabling successful ADC translation / Xiaogang Han, 
       Lindsay King, and Steve Hansel -- Nonclinical pharmacology
       and mechanistic modeling of antibody drug conjugates in 
       support of human clinical trials / Brian J. Schmidt, Chin 
       Pan, Heather E. Vezina, Huadong Sun, Douglas D. Leipold, 
       and Manish Gupta -- Pharmacokinetics of antibody-drug 
       conjugates / Amrita Kamath -- Path to market approval : 
       regulatory perspective of ADC nonclinical safety 
       assessments / Stacey Ricci and Natalie Simpson -- Antibody
       drug conjugates : clinical strategies and applications / 
       Heather E. Vezina, Lucy Lee, Brian J. Schmidt, Manish 
       Gupta -- Antibody-drug conjugates (ADCs) in clinical 
       development / Patricia LoRusso and Joseph McLaughlin -- 
       ADCs approved for use : Trastuzumab emtansine (Kadcyla, T-
       DM1) in patients with previously treated HER2-positive 
       metastatic breast cancer / Gail Lewis Phillips, Sanne de 
       Hass, Sandhya Girish, and Ellie Guardino -- ADCs approved 
       for use : Brentuximab Vedotin / Sven DeVos and Monica Mead
       -- Radioimmunotherapy / Jeffrey Wong and Savita Dandapani 
       -- Radiolabeled antibody-based imaging in clinical 
       oncology / Bart Hendriks and Daniel Gaddy -- Antibody-drug
       conjugates : the next evolution in the cure for cancer -- 
       William C. Olson and Amy Q. Han. 
588    Description based on print version record. 
590    Electronic reproduction. Ann Arbor, MI : ProQuest, 2016. 
       Available via World Wide Web. Access may be limited to 
       ProQuest affiliated libraries. 
650  0 Antibody-toxin conjugates. 
650  0 Monoclonal antibodies. 
650  0 Antineoplastic agents. 
650  0 Tumors|xTreatment. 
655  4 Electronic books. 
700 1  Olivier, Kenneth J.,|cJr.,|d1968-|eeditor. 
700 1  Hurvitz, Sara A.,|d1970-|eeditor. 
776 08 |iPrint version:|aAntibody-drug conjugates (Olivier)
       |tAntibody-drug conjugates : fundamentals, drug 
       development, and clinical outcomes to target cancer.
       |dHoboken, New Jersey : John Wiley & Sons, Incorporated, 
       [2017]|z9781119060680|w(DNLM)101688103 
856 40 |uhttps://ebookcentral.proquest.com/lib/unimelb/
       detail.action?docID=4745624|zConnect to ebook (University 
       of Melbourne only) 
990    Proquest Academic Complete 
990    Batch Ebook load (bud2) - do not edit, delete or attach 
       any records. 
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