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Title Protein targeting / edited by Stella M. Hurtley.

Published Oxford ; New York : IRL Press, [1996]


Location Call No. Status
 UniM BioMed  574.875 PROT    AVAILABLE
Physical description xix, 214 pages : illustrations ; 26 cm.
Series Frontiers in molecular biology ; 16.
Frontiers in molecular biology ; 16.
Bibliography Includes bibliographical references and index.
Contents 1. Targeting precursor proteins to mitochondria / Trevor Lithgow and Gottfried Schatz -- 2. Protein transport to the nucleus and its regulation / David A. Jans -- 3. Targeting and import of peroxisomal proteins / Christopher J. Danpure -- 4. Protein translocation into the endoplasmic reticulum / Karin Romisch and Ann Corsi -- 5. ER - Golgi membrane traffic and protein targeting / Carolyn E. Machamer -- 6. Biogenesis of constitutive secretory vesicles, secretory granules, and synaptic vesicles - facts and concepts / Masato Ohashi, Rudolf Bauerfeind and Wieland B. Huttner -- 7. Protein sorting during endocytosis / Nicholas T. Ktistakis and Michael G. Roth.
Summary This volume addresses one of the fundamental problems of cell biology, namely how proteins are sent to, and maintained at, their correct destinations. Individual chapters provide up-to-date information on protein targeting to different cell organelles; the nucleus, mitochondria, peroxisomes, endoplasmic reticulum, and the Golgi complex. Topics covered include the targeting sequences that act as molecular address tags, the receptors that recognize them, and the role of molecular chaperones. Other chapters focus on how proteins are targeted to organelles that communicate with one another during membrane trafficking in the secretory and endocytic pathways.
Other author Hurtley, Stella M.
Subject Proteins -- Physiological transport.
Proteins -- Secretion.
ISBN 0199635617 (hbk.)
0199635625 (paperback)