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E-RESOURCE

Title Capillary electrophoresis methods for pharmaceutical analysis / edited by Satinder Ahuja, M. llias Jimidar.

Published Amsterdam ; Boston : Elsevier/Academic Press, 2008.

Copies

Location Call No. Status
 UniM INTERNET resource    AVAILABLE
Edition 1st ed.
Physical description 1 online resource (xvi, 529 pages) : illustrations.
Series Separation science and technology, 0149-6395 ; v. 9
Separation science and technology (San Diego, Calif.) ; v. 9.
ScienceDirect All Books
Contents Preface -- 1. Overview of Capillary Electrophoresis in Pharmaceutical Analysis -- 2. Theoretical Consideration in Performance of Various Modes of CE -- 3. Equipment Considerations for Capillary Electrophoresis -- 4. Method Development for Pharmaceutical Analysis -- 5. Role of CE in Drug Substance and Drug Product Development -- 6. General Considerations to Improve Performance of CE Methods -- 7. Overview of Current Regulatory Guidance -- 8. Qualification of CE Instrumentation -- 9. Robustness Testing of CE Methods -- 10. Validation of Analytical Methods -- 11. The Need for CE Methods in Pharmacopeial Monographs -- 12. CE in Impurity Profiling of Drugs -- 13. Ion Analysis -- 14. Role of CE in Biopharmaceutical Development and Quality Control -- 15. Capillary Electrophoresis and Bioanalysis -- 16. CE as Orthogonal Technique to Chromatography -- 17. Capillary Electrochromatography of Pharmaceuticals -- 18. Coupling CE and Chip-based Devices and Mass Spectrometry.
Bibliography Includes bibliographical references and index.
Summary Capillary electrophoresis (CE) is a powerful analytical technique that is widely used in research and development and in quality control of pharmaceuticals. Many reports of highly efficient separations and methods have been published over the past 15 years. CE offers several advantages over high-pressure or high-performance liquid chromatography (HPLC). These include simplicity, rapid analysis, automation, ruggedness, different mechanisms for selectivity, and low cost. Moreover, EC requires smaller sample size and yet offers higher efficiency and thus greater resolution power over HPLC. These characteristics are very attractive in research and development, even more so in pharmaceutical quality control (QC) and stability monitoring (SM) studies. This book will provide busy pharmaceutical scientists a complete yet concise reference guide for utilizing the versatility of CE in new drug development and quality control. - Provides current status and future developments in CE analysis of pharmaceuticals. - Explains how to develop and validate methods. - Includes major pharmaceutical applications including assays and impurity testing.
Other author Ahuja, Satinder, 1933-
Jimidar, M. Ilias.
Elsevier issuing body.
Subject Capillary electrophoresis.
Drugs -- Analysis.
Electronic book.
Electronic books.
ISBN 9780123725738
0123725739
9780080559612 (electronic bk.)
0080559611 (electronic bk.)