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LEADER 00000cam a2200517Ii 4500 
003    OCoLC 
005    20190319055528.2 
006    m     o  d         
007    cr cnu---unuuu 
008    180725s2018    gw a    ob    001 0 eng d 
019    SpringerEBAon1045795541 
020    9783662544976|q(electronic bk.) 
020    3662544970|q(electronic bk.) 
020    |z9783662544969|q(print) 
020    |z3662544962 
024 7  10.1007/978-3-662-54497-6|2doi 
040    GW5XE|beng|erda|epn|cGW5XE|dEBLCP|dN$T|dYDX|dUAB|dOCLCF
       |dMERER|dU3W|dOCLCQ|dLVT|dUPM|dVT2|dCNCEN|dWYU|dCAUOI|dSNK
       |dOCLCQ 
049    MAIN 
050  4 RC71.7 
082 04 616.07/5|223 
245 00 Point-of-care testing :|bprinciples and clinical 
       applications /|cPeter B. Luppa, Ralf Junker (eds.). 
264  1 Berlin, Germany :|bSpringer,|c2018. 
300    1 online resource (xxx, 445 pages) :|bcolor illustrations 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
347    text file|bPDF|2rda 
504    Includes bibliographical references and index. 
505 0  Intro; Preface; About the editors; List of authors; 
       Abbreviations; Definitions and areas of application; 1.1 
       Introduction; 1.2 Terminology and definitions; 1.3 Areas 
       of application; References; The relevance of POCT in 
       healthcare; 2.1 Introduction; 2.2 The medical and 
       financial ­aspects of POCT diagnostics; 2.2.1 Medical 
       aspects; 2.2.2 Economic aspects; 2.3 The POCT market; 
       2.3.1 Problems with market ­valuation; 2.3.2 POCT 
       categories; 2.3.3 Future market trends; References; Device
       classes; 3.1 Introduction; 3.2 Type 1a -- Qualitative POCT
       methods; 3.3 Type 1b -- "Unit-use" POCT systems 
505 8  3.4 Type 2 -- Benchtop POCT ­instruments3.5 Type 3 -- 
       Viscoelastic ­coagulation analyzers; 3.6 Type 4 -- 
       Continuous POCT methods; 3.7 Type 5 -- Molecular 
       biological POCT analyzers; 3.8 Type 6 -- Direct-to-
       consumer testing (DTC); References; Pre- and post-
       analytical ­phases; 4.1 Introduction; 4.2 Pre-analytical 
       phase; 4.2.1 Choosing a suitable test; 4.2.2 Capillary 
       blood sampling; 4.2.3 Venous blood sampling; 4.2.4 
       Arterial blood sampling; 4.2.5 Blood sampling systems and 
       anticoagulants for blood gas analysis; 4.2.6 Blood samples
       from central lines; 4.2.7 Taking swabs; 4.2.8 Urine 
       sampling 
505 8  4.2.9 Inspection of the sample4.2.10 Reliable 
       identification of patient and sample; 4.3 Post-analytical 
       phase; 4.4 Avoiding pre- and ­post-analytical problems; 
       References; Analytical methods, ­biosensor technology; 
       5.1 Biosensor technology; 5.1.1 Sensor (bioreceptor); 
       5.1.2 Transducers, electronic ­amplifiers; 5.1.3 Sample 
       application/fluidic unit; 5.2 Continuous monitoring 
       ­methods; 5.2.1 Continuous monitoring ­methods; 5.2.2 
       Continuous glucose ­monitoring (CGM); References; 
       Laboratory coagulation tests 
505 8  6.2.2 Combined recording of ­plasmatic coagulation, 
       platelet count and fibrinolysis (viscoelastic 
       methods)6.2.3 Analysis of platelet function; 6.2.4 POCT 
       applications with ­coagulation testing methods; 6.3 
       Confounders and influencing variables; 6.4 Quality 
       management; References; Analysis of cellular blood 
       components; 7.1 Introduction; 7.2 Device technology and 
       methods; 7.2.1 POCT blood count analyzers; 7.2.2 Blood gas
       analyzers; 7.2.3 Single analyses; References; Clinical 
       chemistry ­parameters; 8.1 Introduction; 8.2 Device 
       technology and methods; 8.2.1 Dry chemistry; 8.2.2 Wet 
       chemistry 
505 8  8.2.3 Dedicated devices for ­singular analytes8.3 
       Applications and indications; References; Immunological 
       methods; 9.1 Methods; 9.1.1 Immunosensors; 9.1.2 
       Homogeneous and heterogeneous immunoassays; 9.1.3 
       Immunological rapid tests; 9.2 Device format and quality; 
       9.3 Areas of application; 9.3.1 Hospital setting; 9.3.2 
       Physician practice setting; 9.3.3 Home testing; 9.4 
       Aptamers as adjuncts or ­alternatives to antibodies; 
       References; Molecular biological tests; 10.1 Introduction;
       10.2 Integrated and miniaturized systems; 10.3 Selection 
       criteria for POCT systems 
520    The underlying technology and the range of test parameters
       available are evolving rapidly. The primary advantage of 
       POCT is the convenience of performing the test close to 
       the patient and the speed at which test results can be 
       obtained, compared to sending a sample to a laboratory and
       waiting for results to be returned. Thus, a series of 
       clinical applications are possible that can shorten the 
       time for clinical decision-making about additional testing
       or therapy, as delays are no longer caused by preparation 
       of clinical samples, transport, and central laboratory 
       analysis. Tests in a POC format can now be found for many 
       medical disciplines including endocrinology/diabetes, 
       cardiology, nephrology, critical care, fertility, 
       hematology/coagulation, infectious disease and 
       microbiology, and general health screening. Point-of-care 
       testing (POCT) enables health care personnel to perform 
       clinical laboratory testing near the patient. The idea of 
       conventional and POCT laboratory services presiding within
       a hospital seems contradictory; yet, they are, in fact, 
       complementary: together POCT and central laboratory are 
       important for the optimal functioning of diagnostic 
       processes. They complement each other, provided that a 
       dedicated POCT coordination integrates the quality 
       assurance of POCT into the overall quality management 
       system of the central laboratory. The motivation of the 
       third edition of the POCT book from Luppa/Junker, which is
       now also available in English, is to explore and describe 
       clinically relevant analytical techniques, organizational 
       concepts for application and future perspectives of POCT. 
       From descriptions of the opportunities that POCT can 
       provide to the limitations that clinician's must be 
       cautioned about, this book provides an overview of the 
       many aspects that challenge those who choose to implement 
       POCT. Technologies, clinical applications, networking 
       issues and quality regulations are describ ed as well as a
       survey of future technologies that are on the future 
       horizon. The editors have spent considerable efforts to 
       update the book in general and to highlight the latest 
       developments, e.g., novel POCT applications of nucleic 
       acid testing for the rapid identification of infectious 
       agents. Of particular note is also that a cross-country 
       comparison of POCT quality rules is being described by a 
       team of international experts in this field. 
650  0 Point-of-care testing. 
655  4 Electronic books. 
700 1  Luppa, Peter B.,|eeditor. 
700 1  Junker, Ralf,|eeditor. 
710 2  SpringerLink|eissuing body. 
776 08 |cOriginal|z3662544962|z9783662544969|w(OCoLC)972798364 
830  0 Springer Biomedical and Life Sciences eBooks 2018 English+
       International 
856 40 |uhttps://ezp.lib.unimelb.edu.au/login?url=http://
       link.springer.com/10.1007/978-3-662-54497-6|zConnect to 
       ebook (University of Melbourne only) 
990    Springer EBA e-book collections for 2017-2019 
990    Springer Biomedical and Life Sciences eBooks 2018 - Full 
       Set 
990    Batch Ebook load (bud2) - do not edit, delete or attach 
       any records. 
991    |zNEW New collection springerlink.ebooksbls2018 2019-03-18
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