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Title Pituitary Disorders of Childhood : Diagnosis and Clinical Management / editor, Brenda Kohn.

Published Cham, Switzerland : Humana Press, [2019]


Location Call No. Status
Physical description 1 online resource.
Series Contemporary endocrinology
Contemporary endocrinology (Totowa, N.J.)
Springer Medicine eBooks 2019 English+International
Bibliography Includes bibliographical references and index.
Contents Intro; Series Editor Foreword; Preface; Contents; Contributors; Part I: Embryologic and Genetic Disorders of the Pituitary Gland; Chapter 1: Embryologic and Genetic Disorders of the Pituitary Gland; Hypothalamo-Pituitary Development; Human Conditions Arising from Disordered Hypothalamo-Pituitary Development; Isolated Growth Hormone Deficiency; Other Isolated Hormone Deficiencies and Abnormalities; Septo-Optic Dysplasia; HESX1; SOX2 and SOX3; OTX2; GLI2; Pituitary Stalk Interruption Syndrome; ARNT2; PNPLA6; KCNQ1; IFT172; References; Chapter 2: Genetics of Hypopituitarism; Case Presentation
Introduction and Clinical Presentation of Hormone DeficienciesPROP1; POU1F1 (PIT1); Case Continued; Future Considerations; References; Part II: Acquired Pituitary Disorders: Pituitary Tumors and Nonpituitary Sellar Masses; Chapter 3: Adamantinomatous Craniopharyngioma: Genomics, Radiologic Findings, Clinical, and Prognosis; Introduction; Epidemiology; Molecular Aetiology of ACP; Mouse Models of ACP Demonstrate a Causative Role of CTNNB1 Mutations; Sox2+ Pituitary Stem Cells Can Induce Tumour Formation in a Paracrine Manner; Imaging Studies; Presenting Clinical Manifestations
Risk-Adapted Treatment StrategiesSurgery; Radiooncological Treatment; Instillation of Sclerosing Substances for Cystic Tumours; Long-Term Outcome and Morbidities; Pituitary Deficiencies; Visual and Neurological Outcomes; Hypothalamic Syndrome; Challenges in Treating Hypothalamic Obesity; Eating Behaviour; Sequelae, Prognosis, and Quality of Life; Quality of Life, Neurocognitive Outcome, and Psychosocial Functioning; Cerebrovascular Morbidity; Second Malignant Neoplasms; Survival and Late Mortality; Conclusions; References; Chapter 4: Prolactinomas; Introduction and Epidemiology
Presenting Signs and Symptoms of ProlactinomasDiagnostic Approach; Laboratory Evaluation; Evaluation of Elevated Serum Prolactin; Diagnostic Pitfalls in Prolactin Measurement; Considerations in Prolactin Measurement; Falsely Low Prolactin Due to Hook Effect; Macroprolactinemia; Pituitary MRI; Ophthalmological Referral; Consideration of Genetic Testing; Management; Laboratory Evaluation; Observation Without Dopamine Agonist Therapy; Dopamine Agonist Therapy; Adverse Effects; Monitoring Dopamine Agonist Therapy; Weaning Dopamine Agonist Therapy; Surgical Therapy; Other Treatments; Prognosis
Summary References; Chapter 5: Cushing Disease: Diagnosis and Treatment; Introduction; Diagnosis of Cushing Syndrome; History and Physical Examination; Laboratory Evaluation; Assays; Total and Free Cortisol; Urinary Free Cortisol; Low-Dose Dexamethasone Suppression Test; Midnight Serum or Salivary Cortisol Measurement; Identification of the Source of Hypercortisolemia; ACTH Level; CRH Stimulation Test; High-Dose Dexamethasone Suppression Test; Bilateral Inferior Petrosal Sinus Sampling (BIPSS); Imaging Studies; Treatment of CD; Surgical Management; Postoperative Management; Medical Management
Other author Kohn, Brenda, editor.
SpringerLink issuing body.
Subject Pituitary gland -- Tumors.
Tumors in children -- Diagnosis.
Electronic books.
Electronic books.
ISBN 9783030113391 (electronic bk.)
3030113396 (electronic bk.)