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Title Brain tumor immunotherapy [electronic resource] / edited by Linda M. Liau ... [et al.].

Published Totowa, N.J. : Humana Press, c2001.


Location Call No. Status
Physical description 1 online resource (xi, 373 p.) : ill.
Bibliography Includes bibliographical references and index.
Contents Introduction to the disease -- Neuropathology and molecular pathogenesis of primary brain tumors -- Epidemiology of primary brain tumors -- Current therapy for primary brain tumors -- Introduction to immunotherapy of brain tumors -- Immunostimulation and immunomodulation of brain tumors -- Biological principles of brain tumor immunotherapy -- Adoptive cellular immunotherapy of brain tumors -- Systemic T-cell immunotherapy for brain tumors -- Cytotoxic T-lymphocytes reactive to patient major histocompatibility complex proteins for therapy of brain tumors -- Autologous vaccine and adoptive cellular immunotherapy as treatment for brain tumors -- Antibody-mediated immunotherapy of brain tumors -- Anti-idiotype immunotherapy strategies for brain tumors -- Radiolabeled antibodies for therapy of brain tumors -- Immunotoxin therapy of brain tumors -- Antibodies to adhesion molecules for immunotherapy of brain tumors -- Tumor vaccines and other strategies -- Cytokine-based immuno-gene therapy for brain tumors -- Downregulation of transforming growth factor [beta] as therapeutic approach for brain tumors -- Dendritic cell immunotherapy for brain tumors -- Death ligand/death receptor-mediated apoptosis for treatment of brain tumors -- Combining radiation therapy with immunotherapy for treatment of brain tumors.
Summary It is now clear from basic research and clinical trials that immunotherapy for brain tumors is feasible, can evoke relevant biologic responses, and can yield important insights into human biology. In Brain Tumor Immunotherapy, an authoritative panel of researchers and clinicians critically reviews the entire field to provide a comprehensive guide to modern brain tumor immunotherapy and thereby enhance future research in this area. The contributors detail many of the key laboratory experiments and clinical protocols that are currently being investigated, integrate the available information from previous and ongoing research, and help define the current status of the field. Topics range from adoptive cellular and antibody-mediated immunotherapy of brain tumors to tumor vaccines and related strategies, and include many vanguard experimental strategies and immunological techniques for studying tumor immunotherapy. Introductory material brings the reader up-to-date on the biological principles of brain tumor immunotherapy, along with the neuropathology, molecular pathogenesis, epidemiology, and the relevant current therapies. Cutting-edge and comprehensive, Brain Tumor Immunotherapy brings together all the important recent advances in our understanding of central nervous system tumor immunology and illustrates in powerful detail the many new applications now harnessing the immune response for brain tumor therapeutics.
Notes Description based on print version record.
Other author Liau, Linda M.
Subject Brain -- Tumors -- Immunotherapy.
MEDICAL -- Oncology.
Electronic books.
ISBN 9781592590353 (electronic bk.)
1592590357 (electronic bk.)
0896036383 (alk. paper)