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E-RESOURCE

Title Inhibitors of molecular chaperones as therapeutic agents / [edited by] Timothy D. Machajewski, Zhenhai Gao, David Rotella.

Published [Cambridge] : Royal Society of Chemistry, 2013.

Copies

Location Call No. Status
 UniM INTERNET resource    AVAILABLE
Physical description 1 online resource.
Series RSC drug discovery ; volume 37
RSC drug discovery series ; v.37.
Summary This book aims to provide a comprehensive examination of the field of molecular chaperone inhibition and its application to pharmaceutical research. With several small molecule inhibitors in oncology clinical development, there is clearly intense interest in the chaperones as a molecular target. Filling a significant gap in the market by providing a detailed comparison of discovery programs across the industry, this text will find broad interest among researchers in the field of molecular chaperone pharmaceutical research, oncology research, and medicinal chemistry. Arranged into three main sections the book covers structure and function, small molecule inhibitors and concludes with a section discussing clinical perspectives. With specific chapters covering the discovery of key molecules such as, BIIB028, STA-9090, Serenex Hsp90 inhibitor, NVP-AUY922 and NVP-HSP990, this comprehensive text will be an essential treatise for researchers working in academia and industry.
Notes Description based on publisher supplied information.
Other author Machajewski, Timothy D., editor of compilation.
Gao, Zhenhai, editor of compilation.
Rotella, David P., editor compilation.
Subject Molecular chaperones.
Chemical inhibitors.
Electronic books.
ISBN 9781849739689 (electronic bk.)
1849739684 (electronic bk.)
9781849736664
1849736669