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Title Signal transducers and activators of transcription (STATs) : activation and biology / edited by Pravin B. Sehgal, David E. Levy, Toshio Hirano.

Published Dordrecht ; Boston : Kluwer Academic, 2003.


Location Call No. Status
Physical description 1 online resource (xxiv, 746 pages) : illustrations (some color)
Bibliography Includes bibliographical references.
Contents From the Contents: Foreword -- Color Plates -- Introduction -- I: STAT Proteins and their Regulators -- II: Mechanisms of Activation of and Transcriptional Regulation by STAT Proteins -- III: Biological Impact of STAT Activation -- Author Index -- Subject Index.
Summary The year 2003 marked the tenth anniversary of the first use of the acronym "Stat" (also written "STAT") in the scientific literature for a family of transcription factors which rapidly transduce cytokine and growth factor-elicited signals from the plasma membrane to the cell nucleus thereby activating gene transcription (thus, Signal Transducers and Activators of Transcription). The only fully comprehensive reference for what is known about STAT proteins and their biology, this book describes the current state of ongoing research in this broad area, and looks toward the future to try to predict the discoveries that lie ahead. With contributions from the very best experts in the field, it will prove useful to both the novice and the expert, providing a didactic overview of the STAT transcription factor field, a summary of past literature, current developments, and new uncharted, perhaps controversial, ideas and questions about STAT activation and biology.
Notes Description based on print version record.
Other author Sehgal, Pravinkumar B.
Levy, David E.
Hirano, Toshio, 1947-
Subject Transcription factors.
Cellular signal transduction.
Cellular signal transduction.
Transcription factors.
Electronic books.
ISBN 9789401730006 (electronic bk.)
9401730008 (electronic bk.)
Standard Number 10.1007/978-94-017-3000-6