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Title Cartilage regeneration / Yunfeng Lin, editor.

Published Cham, Switzerland : Humana Press, 2017.


Location Call No. Status
Physical description 1 online resource.
Series Stem cell biology and regenerative medicine
Stem cell biology and regenerative medicine.
Springer Biomedical and Life Sciences eBooks 2017 English+International
Notes Includes index.
Contents Chapter 1: Application of€Stem Cells and€the€Factors Influence Their Differentiation in€Cartilage Tissue Engineering; 1.1 Introduction; 1.2 Embryonic Stem Cells; 1.3 Mesenchymal Stem Cells; 1.3.1 Different Sources of€Mesenchymal Stem Cells; Bone Marrow Derived Stem Cells; Adipose Tissue-Derived Stromal Cells; Synovial-Derived Stem Cells; Other Sources of€MSCs; 1.3.2 Comparison Between€Different MSCs in€Cartilage Tissue Engineering; 1.4 Other Kinds of€Stem Cells; 1.4.1 Induced Pluripotent Cells; 1.4.2 Cartilage Progenitor Cells.
1.5 The Factors Influence the€Differentiation of€Stem Cells1.5.1 Co-culture; 1.5.2 Hypoxia; 1.5.3 High-Density Microenvironment; 1.5.4 Growth Factors; 1.5.5 Other Factors Influencing the€Differentiation of€Stem Cells; 1.6 Conclusion; References; Chapter 2: Application of€Scaffold Materials in€Cartilage Tissue Engineering; 2.1 Introduction; 2.2 Ideal Scaffold; 2.3 Materials for€the€Preparation of€Scaffold; 2.3.1 Collagen; 2.3.2 Gelatin; 2.3.3 Hyaluronan; 2.3.4 Fibrin; 2.3.5 Silk Fibers; 2.3.6 Synthetic Polymers; 2.3.7 Acellular Cartilage Matrix; 2.3.8 Polyhydoxyalkanoates (PHA) Family.
3.4 Nano-patterns3.4.1 Nano-patterns Affect Cell Adhesion, Proliferation and€Migration; 3.4.2 Nano-patterns Affect Cell Differentiation; 3.5 Irregular Patterns-Roughness; 3.6 Stiffness; 3.7 Conclusion; References; Chapter 4: Electrospun Fibrous Scaffolds for€Cartilage Tissue Regeneration; 4.1 Electrospinning Materials in€Cartilage Tissue Engineering; 4.2 Topography of€Electrospun Fibrous Scaffold in€Cartilage Tissue Engineering; 4.3 Modifications of€Electrospun Fibrous Scaffold in€Cartilage Tissue Engineering; 4.4 New Electrospinning Approaches in€Cartilage Tissue Engineering.
4.4.1 Dual-Electrospinning4.4.2 Coaxial Electrospinning; 4.4.3 "3D" Electrospinning; 4.5 Prospective; References; Chapter 5: The Research Advances of€Nanomaterials Inducing Osteogenic and€Chondrogenic Differentiation of€Stem Cells; 5.1 Introduction; 5.2 Various Nanomaterials Inducing Osteogenic and€Chondrogenic Differentiation of€Stem Cells; 5.2.1 Inorganic Nanomaterials; Calcium Phosphate Nanocomposites; Carbon Nanomaterials; Silicon Nanoparticles; Iron Oxide Nanoparticles; Gold Nanoparticles; Titanium Nanoparticles.
Bibliography Includes bibliographical references at the end of each chapters and index.
Summary This book focuses on cartilage defects and new mesenchymal stem cell-based treatments for their repair and regeneration. Early chapters provide a review of current etiological findings and repair methods of cartilage defects. The next chapters discuss fundamental concepts and features of MSCs, including their proliferation, differentiation, migration and immunomodulatory effects. The discussion also includes clinical applications of MSCs in cartilage tissues, especially with regards to various animal models, biomaterials and transferring techniques. Cartilage Regeneration focuses on the biology of MSCs and their possible applications in cartilage reconstruction, with the goal of bringing new insights into regenerative medicine. It will be essential reading for researchers and clinicians in stem cells, regenerative medicine, biomedical engineering and orthopedic surgery.
Other author Lin, Yunfeng, editor.
SpringerLink issuing body.
Subject Cartilage -- Regeneration.
Tissue scaffolds.
Electronic books.
Electronic books.
ISBN 9783319516172 (electronic bk.)
3319516175 (electronic bk.)
9783319516165 (print)
Standard Number 10.1007/978-3-319-51617-2