1. Does Life Have a Meaning? The Diversity of Responses. Making Sense of the Question. Incentives for Raising the Question. Critical Junctures in the Life of an Individual. Suffering and Death. Secularization and Spiritual Homelessness. Uses of a World Picture -- 2. Scanning Existence. Dimensions of Reality. Cosmology. Ontology. The Observable Universe. The Observable Region and the Universe as a Whole. Realism and Expanding Horizons. A Conversation with Einstein. Interactive Existents. The Existence of Individuals. Boundless Existence. "Boundless" "That" "Of" Immanence and Transcendence. Summary -- 3. The Locus of Meanings. Interactive Meanings. A Simple Schema. Filling in the Schema. Life Under the Aspect of Boundless Existence. Cosmic Spirituality. Wonder. Consequences. The Rest Is Silence. Summing Up.