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Cover Art
PRINTED BOOKS
Author DeRosa, Thomas F.

Title Advances in synthetic organic chemistry and methods reported in US patents / Thomas F. DeRosa.

Published Amsterdam ; London : Elsevier, 2006.

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Location Call No. Status
 UniM ERC  547.2 DERO    AVAILABLE
Edition 1st ed.
Physical description xv, 696 pages : illustrations ; 25 cm
Notes Formerly CIP. Uk.
Bibliography Includes bibliographical references and index.
Contents Acids and Derivatives 1 -- Aromatic Carboxylic Acid Derivatives 1 -- Azinyloxy, and Phenoxy-Diaryl-Carboxylic Acid Derivatives, Their Preparation and Use as Mixed ETA/ETB Endothelin Receptor Antagonists 5 -- Cinnamic Acid Derivatives 8 -- Compounds Derived from Benzoic Acid Esters, Composition Containing Said Compounds and Use Thereof 12 -- 1,2-Diarylmethylene Derivatives, Their Methods of Preparation, and Their Uses in Therapeutics 14 -- Geranic Acid Derivatives 18 -- Halogenated Cinnamic Acids and Esters Thereof, Processes for the Preparation Thereof and Halogenated Aryldiazonium Salts 20 -- Halogenation Catalyst 22 -- Method for Producing Alkoxy Malonic Acid Dinitriles 24 -- Phosphonosuccinic Acid Derivatives, Processes for Their Preparation and Medicaments Containing These Compounds 26 -- Preparation of Cyclohexane Carboxylate Derivatives 28 -- Water Soluble Fullerenes with Antiviral Activity 33 -- Alcohols 36 -- Butyne Diol Derivatives 36 -- 1,2-Dithin Antiinfective Agents 41 -- Oligiocycloalkanoid Compounds and Methods of Use 44 -- Polymers with Controlled Physical State and Bioerodibility 48 -- 4-Quinolinemethanol Derivatives as Purine Receptor Antagonists 50 -- Synthesis of 5-Decenyl Acetate and Other Pheromone Components 53 -- Aldols 55 -- Stereospecific Synthesis of Aldols 55 -- Aldehydes 58 -- Process for Selective Catalytic Oxidation of Olefins to Aldehydes, Ketones with Cleavage of C=C Bonds 58 -- Alkenes 60 -- Carbonyl-Containing Compounds 60 -- Alkynes 62 -- Diaryl-enynes 62 -- DNA-Cleaving Anti-Tumor Agents 66 -- Amides 70 -- Adamantane Derivatives 70 -- o-Anisamide Derivatives 73 -- Benzamide Analogues Useful as PARP (ADP-Ribosyltransferase, ADPRT) DNA Repair Enzyme Inhibitors 76 -- Carboxamide Compositions, Methods, and Compositions for Inhibiting PARP Activity 79 -- Heterocyclic Amides 82 -- Phosphoramide Compounds 87 -- Amines 90 -- Aminophenyl Ketones Derivatives and a Method for the Preparation Thereof 90 -- Arylamine Synthesis 94 -- Fungicidal Spirocyclic Amines 97 -- Method for Producing Propargylamine Compounds 101 -- One Pot Process for the Preparation of 1-[2-Methylamino-(4-Methoxyphenyl)-Ethyl]Cyclohexanol 104 -- Organic Electroluminescence Device and Phenylenediamine Derivative 106 -- Process for Preparing N-Substituted Hydroxylamines and Salts Thereof 110 -- Sodium Channel Modulators 112 -- Substituted 2-Aminoalkyl 1,4-Diaminobenzene Compounds and Oxidation Dye Precursor Containing the Same 115 -- Aminoacids 117 -- Aminoindanes 117 -- Aminopropylphosphinic Acids 120 -- Cyclic Aminoacids and Derivatives Thereof Useful as Pharmaceutical Agents 122 -- Isocyanoalkyl, Carbonic Acid Derivatives, Their Conversion into Secondary Amidoalkyl Carbonic Acid Derivatives by Isocyanide Multicomponent Reactions, as well as these Secondary Amidoalkyl Carbonic Acid Derivatives 125 -- Spirodiamino Acid Scaffold for Combinatorial Synthesis 128 -- Anthracenones 132 -- 10-Substituted 1,8-Dihydroxy-9(10H) Anthracenone Pharmaceuticals 132 -- Aza and Diaza Bi- and Tricyclics 136 -- Bi- and Tri-Cyclic Aza Compounds and Their Uses 136 -- Certain Tricyclic Substituted Diazabicyclo[3.2.1]octane Derivatives 141 -- Dopamine Transporter Imaging Agent 144 -- N-Alkyl and N-Acyl Derivatives of 3,7-Diazabicyclo-[3.3.1] Nonanes and Selected Salts Thereof as Multiclass Antirrhythmic Agents 147 -- Process for the Manufacture of Tropenol 150 -- Aza Benzazolium Salts 153 -- Aza-Benzazolium Containing Cyanine Dyes 153 -- Aza-Dihydroquinoxaline 156 -- 8-Aza, 6-Aza and 6,8-Diazo-1,4-dihydroquinoxaline-2,3-diones and the Use Thereof as Antagonists for the Glycine/NMDA Receptor 156 -- Aza-Indolyls 159 -- Aza-Indolyl Derivatives for Treating Obesity 159 -- Aza-Oxindoles 162 -- Substituted Aza-Oxindole Derivatives 162 -- Azides 165 -- Stereoselective Ring Opening Reactions 165 -- Aziridines/Diazirines 170 -- Diazirine Derivatives of Aromatic Heterocyclic Compounds 170 -- Preparation of N-Arylmethyl Aziridine Derivatives 1,4,7,10-Tetraazacyclododecane Derivatives Obtained Therefrom and N-Arylethyl-ethanolamine Sulfonate Esters as Intermediates 173 -- Process for Producing Aziridine Compounds 176 -- Benzodiazopines 178 -- Benzodiazepines 178 -- Benzoxazoles 182 -- Benzoxazoles 182 -- Benzopyrans 186 -- Benzopyran Derivatives 186 -- Benzothiophenes 190 -- Pentacyclic Compounds, Intermediates, Processes, Compositions, and Methods 190 -- Benzotriazole 195 -- Method of Synthesizing t-Amido-Substituted 2-(2-Hydroxyphenyl)benzotriazole Compounds in a One-Step Process 195 -- Carbamates/Ureas 199 -- Herbicidal Sulfonylureas, Their Preparation and Use 199 -- Process for the Preparation of Aminocarbonyl Derivatives of Geneseroline Having Selective Brain Anticholinesterase Activity 202 -- Catalysis 205 -- Highly Reactive Form of Copper and Reagents Thereof 205 -- Lewis Acid Catalyst Composition 208 -- Cumulenes 211 -- Aromatic Allene Compounds of the Formula (CH[subscript 2] = CH-O)[subscript n]-R-(A)[subscript m] in Which R is an Aromatic Group and Preparation Thereof 211 -- Preparation of Unsaturated Ketones 214 -- (S)-4-Amino-Hepta-5,6-Dienoic Acid and Intermediates Thereof 217 -- Cyanohydrins 220 -- Method for the Stereoselective Production of Substituted Cyclohexylanhydrins 220 -- Cyclodextrane/Dextrane 223 -- Conjugation of Biomolecules Using Diels-Adler Cycloaddition 223 -- Nohr-McDonald Elimination Reaction 227 -- Cyclopentadiene 230 -- Cyclopentadienyl Derivatives and Process for Their Preparation 230 -- Cyclopropanes 233 -- Aryl Phenylcyclopropyl Sulfide Derivatives and Their Use as Cell Adhesion Inhibiting Anti-Inflammatory and Immune Suppressive Agents 233 -- Cyclic Compounds Having a Cycloalkylene Chain 236 -- 2-Hydroxymethylcyclopropylidene-Methylpurines and -Pyrimidines as Antiviral Agents 240 -- Process of Producing Cyclopropanecarboxylate Compounds 245 -- Process for the Preparation of Methylenecyclopropane 247 -- Synthesis of Cyclopropaneacetylene by a One Pot Process 249 -- Dentrimer 251 -- Dentrimeric Fullerene Derivatives, Process for Their Preparation, and Use as Neurprotectants 251 -- Starburst Conjugates 255 -- Enamines 258 -- Use of Enamines as Light Protection Agents 258 -- Enaminones 261 -- Phenyl-Substituted Cyclic Enaminones 261 -- Ethers 265 -- Diaryl Ether Condensation Reactions 265 -- Preparation and Use of Ionic Liquids in Microwave-Assisted Chemical Transformations 268 -- Wurster's Crown Ligands 270 -- Formazan 272 -- Formazan Metal Complexes 272 -- Furazancarboxylic Acid Derivatives 275 -- Hydroxymethylfurazancarboxylic acid derivatives 275 -- Furanones 278 -- Furanone Derivatives 278 -- Guanidines 280 -- Cyclic Guanidine Derivatives and Their Use as Pesticides 280 -- Guanines 283 -- Substituted O[superscript 6]-Benzyl-8-Aza-Guanines 283 -- Hydrazine 286 -- Diacylhydrazine Derivatives 286 -- Method for Synthesizing Hydrazodicarbonamide 290 -- Imidazole 292 -- Method for Preparing Cycloheptimidazoles 292 -- Substituted Imidazole Compounds 295 -- Imidazolidine 299 -- Cis-Imidazolines 299 -- Spiroimidazolidine Derivatives, Their Preparation, Their use and Pharmaceutical Preparations Formed Therefrom 302 -- Imidazolone 307 -- Fungicidal 2-Imidazolin-5-ones and Imidazoline-5-thiones 307 -- Imidazoltriazionones 311 -- 2-Phenyl Substituted Imidazotriazinones as Phosphodiesterase Inhibitors 311 -- Imide Derivatives 315 -- Photocleavable Agents and Conjugates for the Detection and Isolation of Biomolecules 315 -- Process for the Preparation of Alkyl 4[2-(Phthalimido)ethoxy]-Acetoacetate 320 -- Iminocarboxylic Acid Methyl Amides 322 -- Preparation of [alpha]-Methoxyiminocarboxylic Acid Methylamides and Intermediates Therefore 322 -- Indoles 326 -- Process for the Preparation of Indole Derivatives and Intermediates of the Process 326 -- Synthetic Compounds for Treatment of Inflammation 331 -- Tetrahydro-[beta]-Carbolines 333 -- Indoline 337 -- Amination Process 337 -- Isocoumarins 341 -- Process for Preparing Isocoumarins 341 -- Isoxazolines 345 -- Method for Producing Isoxazoline-3-yl-acyl Benzene 345 -- Ketones 349 -- Acetoacetic Acid Derivatives, Process for Their Preparation and Their Use 349 -- Methods for Making
Substituted Phenylketoenols 352 -- Process for Preparing 3-Hydroxymethyl-4-(Aryl or Heterocyclic)-Cyclopentanones 355 -- Process for Preparing Trifluoromethyl Ketones 360 -- Process for the Preparation of High Purity Alkyladamanantyl Esters 362 -- Lactams 364 -- Anticonvulsant and Anxiolytic Lactam and Thiolactam Derivatives 364 -- [beta]-Lactams as Antiproliferative Agents 367 -- [beta]-Lactam-like Chaperone Inhibitors 371 -- N-Thiolated [beta]-Lactam Antibiotics 373 --
Process for Preparing [beta]-Lactam Compounds 376 -- 6-(Spirocyclopropyl)-Penicillanic Acid-4,4-Dioxides 379 -- Lactones 382 -- Benzylidene-[gamma]-Butryolactones, Process for Their Preparation and Their Use as UV Absorbers 382 -- Ring-Opened Azlactone Initiators for Nitroxide-Mediated Polymerization 385 -- Macocyclic Rings 388 -- [beta]-Diketone Compounds, [beta]-Diketone Compounds Coordinated to Metal, Method of Organic Synthesis with These, and Catalyst 388 -- 1,4-Dioxacylcycloalkane-2-one and 1,4-Dioxacylcycloalkene-2-one 392 -- Synthesis of Macrocyclic Tetraamido-N Ligands 394 -- Preparation of Giant Ring Compounds 397 -- Morpholines 399 -- Lewis Acid-Catalyzed Claisen Rearrangements in the Preparation of Chiral Products 399 -- Naphthopyans 401 -- Indeno-fused Photochromic Naphthopyrans 401 -- Naphthyridines 406 -- 4-Hydroxy-1,8-Naphthyridine-3-Carboxamides as Antiviral Agents 406 -- Nitro Derivatives 410 -- Geminal-Dinitro-1,5-Diazocine Derivatives 410 -- Methods of Preparing Salts of Dinitromethane 416 -- Vicarious Nucleophilic Substitution Using 4-Amino-1,2,4-Triazole, Hydroxylamine or O-Alkylhydroxylamine to Prepare 1,3-Diamino-2,4,6-Trinitrobenzene or 1,3,5-Triamine-2,4,6-Trinitrobenzene 418 -- Nitrones 420 -- Furan Nitrone Compounds 420 -- Organometallics 424 -- Aryl Borates 424 -- Boric Ester Synthesis 427 -- Method for Producing Monoaryloxy-ansa-Metallocenes 429 -- Process for Preparing Bisallylboranes and Non-Aromatic Boronic Acids 432 -- Synthetic Molecules That Specifically React with Target Sequences 434 -- Orthocarbonates, Esters, and Derivatives 437 -- Spiroorthocarbonates Containing Epoxy Groups 437 -- Substituted Sprioalkylamino and Alkoxy Heterocyclics, Processes for Their Preparation, and Their Use as Pesticides and Fungicides 441 -- Synthesis of Spiro Orthoesters, Spiro Orthocarbonates, and Intermediates 444 -- Oxadiazines 447 -- Oxadiazine Derivatives 447 -- 1,3,4-Oxadiazine Derivatives and Their Use as Pesticides 451 -- Oxathiolanes 454 -- Antiviral Activity and Resolution of 2-Hydroxylmethyl-5-(5-fluorocytosin-1-yl)-1,3-Oxathiolane 454 -- Substituted 1,3-Oxathiolanes with Antiviral Properties 458 -- Oxazines 462 -- Photochromic Oxazine Compounds and Methods for Their Manufacture 462 -- Oxazolidinones 465 -- Process to Prepare Cyclic-Sulfur Fluorine Containing Oxazolidinones 465 -- Oxetanes 470 -- Fluorinated Oxetane Derivatives and Production Process Thereof 470 -- Process for the Production of 3-Alkyl-3-Hydroxymethyloxetanes 473 -- Oxetanones 475 -- Oxetanone Derivatives 475 -- Oximes 478 -- O-Acyloxime Photoinitiators 478 -- Oxime Derivatives and Their Use Thereof as Latent Acids 482 -- Oxirane 484 -- Diels-Adler Adducts of Epoxybutene and Epoxybutene Derivatives 484 -- Process for the Preparation of an Oxirane, Aziridine or Cyclopropane 486 -- Phenols 489 -- Calixarene Derivatives 489 -- Dimeric Arylisoquinoline Alkaloids and Synthesis Method Thereof 493 -- Process for Preparing Procyanidin (4 to 6 or 4 to 8) Oligomers and Their Derivatives 497 -- Piperidine 501 -- N-Acyl Cyclic Amine Derivatives 501 -- Opiate Compounds, Methods of Making and Methods of Use 505 -- Process for Production of Piperidine Derivatives (Note 1) 509 -- Spiropiperidine Derivatives 513 -- Piperizines 517 -- Piperazine Derivatives 517 -- Porphyrins 520 -- 1,3-Dipolar Cycloadditions to Polypyrrolic Macrocycles 520 -- Pyrans 522 -- Synthesis of 3,6-Dialkyl-5,6-Dihydro-4-Hydroxy-Pyran-2-One 522 -- Pyrazoles 525 -- Parasiticidal Compounds 525 -- Spiropyrazole Compounds 529 -- Pyridine 532 -- Process for Preparing Tribromomethylsulfonylpyridine 532 -- 3-Pyridinyl Compounds 534 -- Pyridone and Tetrahydropyridone 537 -- Pyridone Derivatives, Their Preparation and Their Use as Synthesis Intermediates 537 -- Solid Phase Synthesis of Heterocycles 542 -- Pyrimidines 545 -- N-Heterocyclic Derivatives as NOS Inhibitors 545 -- Pyrrols 548 -- 7-Azabicyclo[2.2.1]Heptane and Heptene Derivatives as Cholinergic Receptor Ligands 548 -- Colormetric Sensor Compositions and Methods 552 -- Quinones 555 -- Compositions and Methods for Treating Viral Infections 555 -- Quinone Compound, Liquid Crystal Composition, and Guest-Host-Type Liquid Crystal Cell Employing the Same 559 -- Polycyclic Aryl and Heteroaryl Substituted 1,4-Quinones Useful for Selective Inhibition of the Coagulation Cascade 562 -- Synthesis of Coenzyme Q10 (Ubiquinone) 566 -- Radiolabelled Reagents 570 -- Radioligands and Their Use for Identifying Potassium Channel Modulators 570 -- Synthesis of [superscript 2]H- and [superscript 13]C-Substituted Dithanes 574 -- Tritioacetylating Reagents and Processes for Preparation Thereof 576 -- Saccharides 578 -- 2-Saccharinylmethyl Heterocyclic Carboxylates Useful as Proteolytic Enzyme Inhibitors and Compositions and Method of Use Thereof 578 -- Sugars 583 -- Heavily Fluorinated Sugar Analogues 583 -- Preparation of Thioarabinofuranosyl Compounds and Use Thereof 587 -- Process for the Alkaline Oxidative Degradation of Reducing Sugars 591 -- Sugar Derivatives of Hydromorphorine, Dihydromorphorine and Dihydroisomorphorine Compositions Thereof and Uses for Treating or Preventing Pain 594 -- Sulfonamides 597 -- Thioaryl Sulfonamide Hydroxamic Acid Compounds 597 -- Sulfones 602 -- [alpha]-Amino-[beta]-Sulfonyl Hydroxamic Acid Compounds 602 -- Nitromethylthiobenzene Derivatives as Inhibitors of Aldose Reductase 605 -- Process for the Preparation of Ethanesulfonyl-piperidine Derivatives 608 -- [alpha],[beta]-Unsaturated Sulfones for Treating Proliferative Disorders 612 -- Sulfonylimides 615 -- Sulfonylimide Compounds 615 -- Tetrabenazine 618 -- Iodine Derivatives of Tetrabenazine 618 -- Tetracyclines 621 -- 7-Substituted Fused Ring Tetracycline Compounds 621 -- Tetrahydrobenzoquinoxaline Diones 624 -- Pyrrolyl Tetrahydrobenzoquinoxaline Diones, Their Preparation and Use As Glutamate Receptor Antagonist 624 -- Tetrahydrobenzothiepines 628 -- Method for the Preparation of Tetrahydrobenzothiepines 628 -- Tetrahydroisoquinolines 633 -- Pictet-Spengler Reaction for the Synthesis of Tetrahydroisoquinolines and Related Heterocyclic Compounds 633 -- Tetrahydroquinolines 635 -- Dimeric Compounds 635 -- Tetrazoles 638 -- Tetrazolyl-Phenyl Actamide Glucokinase Activators 638 -- Thiazoles 643 -- Oxazolo, Thiazolo and Selenazolo [4,5-c]-Quinolin-4-Amines and Analogues Thereof 643 -- Tri-Aryl-Substituted-Ethane PDE4 Inhibitors 646 -- Thiophenes 651 -- 3,4-Diaryl Thiopenes and Analogs Thereof Having Use as Anti-inflammatory Agents 651 -- Oligiothiophenes and Synthesis Thereof 655 -- Polyaryl Antitumor Agents 658 -- Triazines 661 -- Aryloxy- and Arylthio-substituted Pyrimidines and Triazines and Derivatives Thereof 661 -- Method of Alkylating Triazine Derivatives 665 -- Triazoles 668 -- One Step Synthesis of 1,2,3-Triazole Carboxylic Acids 668 -- Triazolyl-Tetrazinyl-Aminotriazine Compounds Useful in Pyrotechnic Compositions and Process Thereof 671 -- Trioxolanes 674 -- Spiro and Dispiro 1,2,4-Trioxolane Antimalarials 674.
Summary "Advances in Synthetic Organic Chemistry and Methods Reported in US Patents provides synthetic guidelines for preparing current and commercially significant organic compounds, derivatives, and intermediates as reported in issued US Patents. Industries surveyed include agrochemical, cosmetics and personal care products. Each entry contains extensive information such as explicit laboratory directions for preparing all chemical intermediates and characterization data. Furthermore, product optimization studies, industrial preparation, and new synthetic methods have been included for selected entries, as well as projected research directions for future product development. In Advances in Synthetic Organic Chemistry and Methods Reported in US Patents the author's practical approach enables readers to identify research and market trends, and stay up-to-date on current developments in the field."--Publisher's website.
Subject Organic compounds -- Synthesis.
Organic compounds -- Synthesis -- Patents.
Patents -- United States.
ISBN 9780080444741 : No price
0080444741 : No price