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Title Gene expression in recombinant microorganisms / edited by Alan Smith.

Published New York : M. Dekker, [1995]


Location Call No. Status
 UniM BioMed ST  660.65 GENE    AVAILABLE
Physical description xii, 410 pages : illustrations ; 24 cm.
Series Bioprocess technology ; 22.
Bioprocess technology ; v. 22.
Bibliography Includes bibliographical references and index.
Contents 1. Gene Expression in Recombinant Escherichia coli / Joan Stader -- 2. Gene Expression in Recombinant Bacillus / Matti Sarvas -- 3. Gene Expression in Recombinant Yeast / Albert Hinnen, Frank Buxton, Bhabotosh Chaudhuri, Jutta Heim, Thomas Hottiger, Bernd Meyhack and Gabriele Pohlig -- 4. Gene Expression in Methylotrophic Yeasts / Gerd Gellissen, Cornelis P. Hollenberg and Zbigniew A. Janowicz -- 5. Gene Expression in Filamentous Fungi: Expression of Pectinases and Glucose Oxidase in Aspergillus niger / Jaap Visser, Henk-Jan Bussink and Cor Witteveen -- 6. Gene Expression in Recombinant Streptomyces / Richard H. Baltz -- 7. Recombinant Microorganisms: Safety and Regulatory Aspects / Anthony J. Taylor.
Summary Describing the scientific and commercial applications of microbial recombinant DNA technology, this outstanding, single-source reference offers state-of-the-art reviews of gene expression in the most important classes of recombinant microorganisms -- providing numerous examples of the expression of homologous genes or heterologous gene products. Detailing various aspects of metabolic regulation and fermentation process technology, Gene Expression in Recombinant Microorganisms considers the basic biology and gene expression of Escherichia coli ... examines the gene expression system based on the indigenous 2-[mu]m plasmid of the yeast Saccharomyces cerevisiae ... elucidates the exploitation of the strongly inducible promoters associated with the growth of methylotrophic yeasts on methanol ... documents the fungal expression system based on the knowledge established for Aspergillus nidulans and Neurospora crassa ... analyzes gene expression and regulation in Streptomyces ... presents a unique collection of safety and regulatory considerations from around the world ... addresses specific measures to be taken for large-scale industrial operations ... speculates on future prospects and developments in biopharmaceutical research ... and much more. Thoroughly referenced, furnishing over 1400 literature citations, Gene Expression in Recombinant Microorganisms is an invaluable resource for biotechnologists, biochemists, applied and industrial microbiologists, molecular and cell biologists, virologists, bacteriologists, mycologists, microbial geneticists, bioprocess and chemical engineers, fermentation and regulatory affairs specialists, biosafety and research managers, and upper-level undergraduate and graduate students in these disciplines.
Other author Smith, Alan, 1943-
Subject Microbial genetics.
Recombinant microorganisms.
Gene expression.
Genetic engineering -- Methodology.
ISBN 0824795431 (acid-free)