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Cover Art
Author Wostmann, Bernard S.

Title Germfree and gnotobiotic animal models : background and applications / Bernard S. Wostmann.

Published Boca Raton : CRC Press, [1996]


Location Call No. Status
 UniM BioMed ST  591.0724 WOST    AVAILABLE
Physical description 189 pages : illustrations ; 24 cm
Bibliography Includes bibliographical references and index.
Contents Ch. I. Introduction -- Ch. II. Early Growth, Body Weight, Reproduction, and Life Span -- Ch. III. Anatomy, Morphology, and Function of the Gastrointestinal System -- Ch. IV. Morphology and Physiology, Endocrinology and Biochemistry -- Ch. V. Nutrition -- Ch. VI. The Chemically Defined Diet -- Ch. VII. Immunology, Including Radiobiology and Transplantation -- Ch. VIII. Parasitology -- Ch. IX. Pathology Over the Life Span of the Germfree Rat and the Germfree Mouse -- Ch. X. Applications: Past, Present, and Future. Part I -- Ch. XI. Applications: Past, Present, and Future. Part II. Use of the Gnotobiote in the Study of Disease -- Ch. XII. Applications: Past, Present, and Future. Part III. The Production of Monoclonal Antibodies and Conclusions.
Summary The germfree animal is reared in the laboratory to be bacteria free; its counterpart, the gnotobiotic animal, is exposed to select microorganisms. These animal models are used extensively in biomedical research to study the effects of specific microorganisms on the host animal. Germfree and Gnotobiotic Animal Models brings together the most notable points of early and recent studies and gives reference to the most pertinent literature.
Subject Laboratory animals.
Germfree animals.
Diseases -- Animal models.
ISBN 084934008X (acid=paper)