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Book Cover
Author Dean, Ann, speaker.

Title The Beta-globin locus / Ann Dean.

Published London : Henry Stewart Talks, 2014.


Location Call No. Status
Physical description 1 online resource (1 streaming video file (35 minutes) : color, sound).
polychrome rdacc
Series Epigenetics, chromatin, transcription and cancer, 2056-452X.
Eukaryotic gene regulation : from chromatin to transcription to mRNA processing, 2056-452X.
Henry Stewart talks. Biomedical & life sciences collection. Epigenetics, chromatin, transcription and cancer.
Henry Stewart talks. Biomedical & life sciences collection. Eukaryotic gene regulation : from chromatin to transcription to mRNA processing.
Notes Animated audio-visual presentation with synchronized narration.
Revised version of talk first published in 2007.
Title from title frames.
Contents Contents: The globin loci encode hemoglobin subunits -- Erythrocytes & hemoglobin -- Human globin genes and hemoglobins -- Globin gene expression during development -- Globin gene structure -- Sickle cell disease -- Beta-thalassemia -- Transcriptional regulation by recruitment (Enhancers, Silencers and Insulators) -- Chromatin conformation capture (3C) assay -- Chromatin looping in the beta-globin locus -- The LDB1 complex in erythroid cells -- Nuclear re-location of the beta-globin locus -- Natural mutations and hemoglobin switching -- BCL11A, beta-globin and gamma-globin expression -- Interfering with BCL11A silencing.
Restrictions Access restricted to subscribers.
System notes Mode of access: World Wide Web.
System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v2.1+, iPhone 4+ (iOS v5.x+), iPad 2+ (iOS v5.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+.
Subject Epigenesis.
Genetic regulation.
Genetic transcription -- Regulation.
Sickle cell anemia.
Variant Title β-globin locus.
Publisher Number 1004 Henry Stewart Talks