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Author Grune, Tilman, speaker.

Title Protein oxidation and removal of oxidized proteins by proteolysis / Tilman Grune.

Published London : Henry Stewart Talks, 2007.


Location Call No. Status
Physical description 1 streaming video file (39 minutes) : digital, mono, SWF file, sound, colour.
polychrome rdacc
Series Free radicals and the oxygen paradox : oxidative stress in biology, aging and disease.
Henry Stewart talks. Biomedical & life sciences collection. Free radicals and the oxygen paradox : oxidative stress in biology, aging and disease.
Notes Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents Contents: Oxidized proteins -- Intracellular proteases -- The 20S core proteasome -- Proteasomal particles -- The proteasome-ubiquitin system -- Protein oxidation and proteasome -- Degradation of oxidized proteins and protein function -- Protein surface hydrophobicity -- Unfolding of oxidized proteins -- Stability of the 20S proteasome towards oxidation -- Oxidative stress and protein turnover -- Oxidation-induced proteolysis -- Degradation of oxidized proteins in cells -- What happens if degradation fails? -- Protein aggregates inhibit the proteasome -- Particle uptake by fibroblasts.
Restrictions Access restricted to subscribers.
System notes Mode of access: World Wide Web.
System requirements: Operating System: PC Windows 2000+, Mac OSX+ 3.2. Browser Compatibility: IE6+, Firefox 2+, Opera 9+, Safari 2+ 3.3. Browser settings: enable JavaScript, enable popups from the Henry Stewart Talks site. 3.4. Required Browser Plugins & Viewers: Adobe (Macromedia) Flash Player 7+, Adobe Acrobat Reader 6.0+.