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Author Pyle, Anna Marie, speaker.

Title Self-splicing intron RNAs : ribozymes, parasites and agents of genomic change / Anna Marie Pyle.

Published London : Henry Stewart Talks, 2007.


Location Call No. Status
Physical description 1 streaming video file (59 minutes) : digital, mono, SWF file, sound, colour.
polychrome rdacc
Series From DNA to proteins : the multiple levels of regulation.
Henry Stewart talks. Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.
Notes Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents Contents: Different classes of introns -- Autocatalytic group I and group II introns -- Discovery of self-splicing -- Converting a self-splicing RNA into a multiple-turnover enzyme -- The "tetrahymena ribozyme" and discovery of RNA catalysis -- New insights into molecular recognition of RNA -- Group I intron structure and catalytic mechanism -- Group I intron applications -- Group II introns and the big picture -- Discovery of self-splicing by group II introns -- Chemical mechanism of group II intron reactions -- Catalytic engines for driving eukaryotic evolution -- Explaining specificity of group II ribozymes -- Group II intron ribozymes as model systems for RNA folding -- Group II ribozymes as model systems for RNA tertiary structure -- Nucleotide analog interference mapping -- Current map of important atoms -- Nucleotide analog interference suppression -- Lambda-lambda interaction -- 3D model of ai5gamma intron -- Group II introns as tools and therapeutics.
Restrictions Access restricted to subscribers.
System notes Mode of access: World Wide Web.
System requirements: Operating System: PC Windows 2000+, Mac OSX+ 3.2. Browser Compatibility: IE6+, Firefox 2+, Opera 9+, Safari 2+ 3.3. Browser settings: enable JavaScript, enable popups from the Henry Stewart Talks site. 3.4. Required Browser Plugins & Viewers: Adobe (Macromedia) Flash Player 7+, Adobe Acrobat Reader 6.0+.
Variant Title Title on publisher web site: Splicing of group I and II introns.