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Author Rodnina, Marina V., speaker.

Title Elongation of protein synthesis : structural basis of the peptide bond / Marina V. Rodnina.

Published London : Henry Stewart Talks, 2007.


Location Call No. Status
Physical description 1 streaming video file (40 minutes) : digital, mono, SWF file, sound, colour.
polychrome rdacc
Series From DNA to proteins : the multiple levels of regulation.
Henry Stewart talks. Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.
Notes Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents Contents: The ribosome -- Chemistry of peptide bond formation -- Structure of the peptidyl transferase center of the ribosome -- Structures of the catalytic subunit with reaction substrates and transition state analogs -- Induced fit in peptide bond formation and peptidyl-tRNA hydrolysis -- Reaction pathways of catalyzed and uncatalyzed reactions -- pH dependence of catalysis -- Entropic catalysis -- Role of active site residues -- Importance of 2' OH of A76 of the tRNA in the P site -- The mechanism of peptide bond formation.
Restrictions Access restricted to subscribers.
System notes Mode of access: World Wide Web.
System requirements: Operating System: PC Windows 2000+, Mac OSX+ 3.2. Browser Compatibility: IE6+, Firefox 2+, Opera 9+, Safari 2+ 3.3. Browser settings: enable JavaScript, enable popups from the Henry Stewart Talks site. 3.4. Required Browser Plugins & Viewers: Adobe (Macromedia) Flash Player 7+, Adobe Acrobat Reader 6.0+.