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Cover Art
Author Marchuk, Guri I.

Title Mathematical Modelling of Immune Response in Infectious Diseases [electronic resource] / by Guri I. Marchuk.

Published Dordrecht : Springer Netherlands, 1997.


Location Call No. Status
Physical description 1 online resource (x, 350 pages).
Series Mathematics and Its Applications ; 395
Mathematics and Its Applications ; 395.
Summary This is the first monograph to present a unified approach to using mathematical models in the study of qualitative and quantitative regularities of immune response dynamics in infectious diseases within individual organisms. These mathematical models are formulated as systems of delay- differential equations. Simple mathematical models of infectious diseases, antiviral immune response and antibacterial response were developed and applied to the study of hepatitis B, influenza A, infectious bacterial pneumonia, and mixed infections. Particular attention was paid to the development of efficient computational procedures for solving the initial value problem for stiff delay-differential equations and to the parameter identification problem. Adjoint equations and the perturbation theory were used for the sensitivity analysis. Audience: This book will be of interest to a wide range of mathematicians and specialists in immunology and infectious diseases. It can also be recommended as a textbook for postgraduate students, bridging the gap between mathematics, immunology and infectious diseases research.
Subject Mathematics.
Emerging infectious diseases.
Systems theory.
Computer science -- Mathematics.
Electronic books.
ISBN 9789401587983 (electronic bk.)
9401587981 (electronic bk.)