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Title Therapeutic oligonucleotides : methods and protocols / edited by John Goodchild.

Published New York : Humana Press : Springer, [2011]


Location Call No. Status
 UniM BioMed ST  574.88078 METH  v.764    AVAILABLE
Physical description xi, 340 pages : illustrations ; 27 cm.
Series Methods in molecular biology, 1064-3745 ; 764.
Springer protocols.
Methods in molecular biology (Clifton, N.J.) ; v. 764.
Springer protocols (Series)
Bibliography Includes bibliographical references and index.
Contents Therapeutic oligonucleotides / John Goodchild -- Dinucleotides containing 3-S-phosphorothiolate linkages / James W. Gaynor and Richard Cosstick -- 2-O,4-C-methyleneoxymethylene bridged nucleic acids (2,4-BNACOC) / Yoshiyuki Hari ... [et al.] -- Non-covalent peptide-based strategy for ex vivo and in vivo oligonucleotide delivery / Laurence Crombez ... [et al.] -- Cell-penetrating peptides-based strategies for the delivery of splice redirecting antisense oligonucleotides / Samir El Andaloussi ... [ et al.] -- Nanoparticle for tumor targeted delivery of oligomers / Xinrong Liu, Yi Wang, and Donald J. Hnatowich -- Light-directed delivery of nucleic acids / Sigurd Bøe ... [et al.] -- Antibody targeted siRNA delivery / Masoud M. Toloue and Lance P. Ford -- Aptamer-drug conjugation for targeted tumor cell therapy / Michael J. Donovan ... [et al.] -- Five-step process for screening antisense compounds for efficacy: gene target IL-12Rb2 / Nikki B. Marshall, Laura L. Hauck, and Dan V. Mourich -- Diverse small non-coding RNAs in RNA interference pathways / Liande Li and Yi Liu -- Quantification of siRNAs in vitro and in vivo / Angie Cheng, Alexander V. Vlassov, and Susan Magdaleno -- Optimization of transfection conditions and analysis of siRNA potency using real-time PCR / Angie Cheng, Susan Magdaleno, and Alexander V. Vlassov -- siRNA knockdown of gene expression in endothelial cells / Emily Dennstedt and Brad Bryan -- Using RNA interference in Schistosoma mansoni / Rita Bhardwaj, Greice Krautz-Peterson, and Patrick J. Skelly -- Performing the labeled microRNA pull-down (LAMP) assay system : an experimental approach for high-throughput identification of microRNA-target mRNAs / Ren-Jun Hsu and Huai-Jen Tsai -- Synthesis, purification, and characterization of oligoribonucleotides that act as agonists of TLR7 and/or TLR8 / Tao Lan and Ekambar R. Kandimalla -- Synthesis, purification, and characterization of immune-modulatory oligodeoxynucleotides that act as agonists of toll-like receptor 9 / Mallikarjuna Reddy Putta, Dong Yu, and Ekambar R. Kandimalla -- Surface plasmon resonance investigation of RNA aptamer-RNA ligand interactions / Carmelo Di Primo, Eric Dausse, and Jean-Jacques Toulme -- Practical considerations for analyzing antigene RNAs (agRNAs) : RNA immunoprecipitation of argonaute protein / Jacob C. Schwartz and David R. Corey -- Inhibition of human papillomavirus expression using DNAzymes / Maria Luisa Benitez-Hess, Pablo Reyes-Gutierrez, and Luis Marat Alvarez-Salas.
Other author Goodchild, John, 1945-
Subject Oligonucleotides -- Therapeutic use.
ISBN 1617791873