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Cover Art
E-RESOURCE
Author Cragg, Peter J.

Title Supramolecular chemistry [electronic resource] : from biological inspiration to biomedical applications / by Peter J. Cragg.

Published Dordrecht ; London : Springer, 2010.

Copies

Location Call No. Status
 UniM INTERNET resource    AVAILABLE
Physical description 1 online resource.
Contents Note continued: 3.3.2. Boxes with Metal Hinges -- 3.3.3. Capsules as Reaction Flasks -- 3.3.4. More Complex Geometries -- 3.4. Synthetic Cells -- 3.4.1. Capsules with Mineral Walls -- 3.4.2. Polymer Based Capsules -- 3.4.3. Lipid Capsules -- 3.4.4. Capsid Virus Mimetics -- 3.5. Towards a Minimal Synthetic Cell -- 3.6. Cellular Aggregation -- 3.7. Summary -- References -- 4.1. Enzymes -- 4.2. Metal Complexes as Enzyme Mimics -- 4.3. Enzymes and Their Supramolecular Analogues -- 4.3.1. Haemoglobin, Myoglobin and Their Models -- 4.3.2. Cytochromes -- 4.3.3. Protection from Radicals: Catalytic Pro- and Antioxidants -- 4.3.4. Copper-Containing Enzymes -- 4.3.5. Zinc-Containing Enzymes -- 4.3.6. Photosynthesis and Artificial Leaves -- 4.3.7. Cyclodextrins as Artificial Enzyme Supports -- 4.3.8. Model Enzymes that do not Require Metals -- 4.3.9. Molecularly Imprinted Polymers -- 4.3.10. Combinatorial Polymers -- 4.3.11. Dynamic Combinatorial Libraries -- 4.4. De novo Design and Evolutionary Development of Enzymes -- 4.5. Summary -- References -- 5.1. Cells and Their Membranes -- 5.1.1. Cell Membranes -- 5.1.2. Transmembrane Migration: Molecular Shuttles -- 5.2. Transmembrane Channels: Selectivity and Gating Mechanisms -- 5.2.1. Voltage Gating -- 5.2.2. Ligand Gating -- 5.2.3. Gating by Aggregation. -- 5.2.4. Gating by p1-1 and Membrane Tension -- 5.2.5. Light Gating -- 5.3. Channel Architecture -- 5.3.1. Channels for Neutral Molecules -- 5.3.2. Anion Channels -- 5.3.3. Cation Channels -- 5.4. Structural Determination -- 5.5. Measuring Channel Activity -- 5.5.1. Voltage Clamping -- 5.5.2. Patch Clamping -- 5.5.3. Bilayer Methods -- 5.5.4. Dye Release Methods -- 5.5.5. NMR Methods -- 5.6. Transmembrane Transport by Artificial Systems -- 5.6.1. Transporters -- 5.6.2. Channel-Forming Systems --
Note continued: 5.7. Summary -- References -- 6.1. Applications of Supramolecular Chemistry in Medical Diagnostics -- 6.2. Design Principles -- 6.3. Supramolecular Sensors -- 6.3.1. Optical and Fluorescent Biosensors -- 6.3.2. Electrochemical Sensors -- 6.4. Macrocyclic Complexes for Imaging -- 6.5. In vivo Imaging: Magnetic Resonance Imaging Agents -- 6.6. Other Supramolecular Sensors -- 6.7. Summary -- References -- 7.1. Therapeutic Applications of Supramolecular Chemistry -- 7.2. Chelation Therapy -- 7.2.1. Desferrioxamine -- 7.2.2. Copper Imbalance: Wilson's Disease and Menke's Syndrome -- 7.3. Macrocyclic Complexes for Radiotherapy -- 7.4. Photodynamic Therapy -- 7.5. Texaphyrins -- 7.6. Targeting Cancer with Peptides -- 7.7. Drug Delivery and Controlled Release -- 7.8. Cyclams as Anti-HIV Agents -- 7.9. Supramolecular Solution to Alzheimer's Disease? -- 7.10. Calixarenes as Therapeutic Agents -- 7.11. Supramolecular Antibiotics -- 7.12. Summary -- References -- 8.1. Bionanotechnology -- 8.2. Unnatural Chemistry of DNA -- 8.3. Molecular Muscles -- 8.4. Nanomedicine -- 8.4.1. Labelling with Nanoparticles -- 8.4.2. DNA Fingerprinting -- 8.4.3. Full Genome Sequencing -- 8.4.4. DNA Sequencing in Real Time -- 8.4.5. Therapeutic Multimodal Nanoparticles -- 8.5. Cell Mimics as Drug Delivery Vehicles -- 8.5.1. Polymer Encapsulated siRNA Delivery -- 8.5.2. Drug Delivery by Particle Disintegration -- 8.5.3. Minicells as Drug Delivery Systems -- 8.6. Supramolecular Protein Engineering -- 8.7. Antimicrobial Limpet Mines -- 8.8. Future Directions -- 8.8.1. Medicinal Nanodevices -- 8.8.2. Powering Nanodevices -- 8.8.3. Functional Nanodevices -- 8.8.4. Verification of Treatment -- 8.8.5. Nanodevice Control -- 8.9. Supramolecular Chemistry and Nanomedicine -- References.
Notes Description based on print version record.
Subject Supramolecular chemistry.
Electronic books.
ISBN 9789048125821
9048125820
Publisher Number 12099603