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Title Analysis of complex disease association studies : a practical guide / edited by Eleftheria Zeggini, Andrew Morris.

Published Amsterdam : Elsevier, 2011.


Location Call No. Status
Edition 1st ed.
Physical description 1 online resource (viii, 331, [11] pages of color plates) : color illustrations
Bibliography Includes bibliographical references and index.
Contents Front Cover; Analysis of Complex Disease Association Studies; Copyright; Table of Contents; List of Contributors; Chapter 1 Genetic Architecture of Complex Diseases; Chapter 2 Population Genetics and Linkage Disequilibrium; Chapter 3 Genetic Association Study Design; Chapter 4 Tag SNP Selection; Chapter 5 Genotype Calling; Chapter 6 Data Handling; Chapter 7 Data Quality Control; Chapter 8 Single-locus Tests of Association for Population-based Studies; Chapter 9 Effects of Population Structure in Genome-wide Association Studies; Chapter 10 Genotype Imputation.
Summary According to the National Institute of Health, a genome-wide association study is defined as any study of genetic variation across the entire human genome that is designed to identify genetic associations with observable traits (such as blood pressure or weight), or the presence or absence of a disease or condition. Whole genome information, when combined with clinical and other phenotype data, offers the potential for increased understanding of basic biological processes affecting human health, improvement in the prediction of disease and patient care, and ultimately the realization of the pr.
Language notes English.
Other author Zeggini, Eleftheria.
Morris, Andrew.
Subject Diseases.
Human genetics.
ISBN 9780123751430 (electronic bk.)
0123751438 (electronic bk.)

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