| Edition |
5th ed. |
| Physical description |
xii, 797 pages : illustrations ; 28 cm |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
3. How drugs act: molecular aspects 22 -- 4. Cellular mechanisms: excitation, contraction and secretion 51 -- 5. Cellular mechanisms: cell proliferation and apoptosis 69 -- 6. Method and measurement in pharmacology 80 -- 7. Absorption and distribution of drugs 91 -- 8. Drug elimination and pharmacokinetics 106 -- Section 2 Chemical Mediators -- 9. Chemical mediators and the autonomic nervous system 122 -- 10. Cholinergic transmission 136 -- 11. Noradrenergic transmission 161 -- 12. Other peripheral mediators: 5-hydroxytryptamine and purines 184 -- 13. Peptides and proteins as mediators 198 -- 14. Nitric oxide 208 -- 15. Local hormones, inflammation and immune reactions 217 -- 16. Anti-inflammatory and immunosuppressant drugs 244 -- Section 3 Drugs Affecting Major Organ Systems -- 17. Heart 264 -- 18. Vascular system 285 -- 19. Atherosclerosis and lipoprotein metabolism 306 -- 20. Haemostasis and thrombosis 314 -- 21. Haemopoietic system 330 -- 22. Respiratory system 340 -- 23. Kidney 352 -- 24. Gastrointestinal tract 367 -- 25. Endocrine pancreas and the control of blood glucose 380 -- 26. Obesity 394 -- 27. Pituitary and adrenal cortex 404 -- 28. Thyroid 421 -- 29. Reproductive system 429 -- 30. Bone metabolism 446 -- Section 4 Nervous System -- 31. Chemical transmission and drug action in the central nervous system 456 -- 32. Amino acid transmitters 462 -- 33. Other transmitters and modulators 474 -- 34. Neurodegenerative disorders 490 -- 35. General anaesthetic agents 503 -- 36. Anxiolytic and hypnotic drugs 515 -- 37. Antipsychotic drugs 525 -- 38. Drugs used in affective disorders 535 -- 39. Antiepileptic drugs 550 -- 40. Analgesic drugs 562 -- 41. CNS stimulants and psychotomimetic drugs 585 -- 42. Drug dependence and drug abuse 594 -- 43. Local anaesthetics 612 -- Section 5 Drugs Used in the Treatment of Infections and Cancer -- 44. Basic principles of chemotherapy 620 -- 45. Antibacterial drugs 635 -- 46. Antiviral drugs 654 -- 47. Antifungal drugs 666 -- 48. Antiprotozoal drugs 672 -- 49. Anthelminthic drugs 687 -- 50. Cancer chemotherapy 693 -- Section 6 Special Topics -- 51. Individual variation and drug interaction 712 -- 52. Harmful effects of drugs 724 -- 53. Gene therapy 738 -- 54. Drug discovery and development 747. |
| Summary |
Pharmacology is now firmly established as a world wide best-selling and highly acclaimed textbook for medical and science students. Its successful approach emphasies the mechanisms by which drugs act and relates these to the overall pharmacological effects and clinical uses. It sets out for the reader a clear route from a molecular understanding of receptors and drug actions, to the therapeutic uses of the most important groups of drugs. For the Fifth Edition the text has been completely updated, incorporating significant new information published in the last few years, while obsolete material has been removed. New agents are fully discussed as well as extensions of basic knowledge which presage further drug development. |
| Other author |
Dale, M. Maureen.
|
|
Ritter, James.
|
|
Moore, P. K. (Philip Keith), 1954-
|
| Subject |
Pharmacology.
|
|
Chemotherapy.
|
| ISBN |
0443071454 |
|
